Objective To explore the effect of evidence-based nursing in preventing lower extremity deep venous thrombosis（DVT） in patients with cerebral hemorrhage.Methods One hundred and forty patients with cerebral hemorrhage admitted to a hospital in Henan Province from October 2018 to October 2020 were selected for the study.The patients were assigned to a control group（n=68） and an observation group（n=72） using the random number table method.Patients in the control group received conventional care.Patients in the observation group received the evidence-based nursing intervention after receiving conventional care.The incidence of DVT in the lower extremities of patients in the 2 groups was compared after the intervention.The coagulation function indexes before and after the intervention were compared between the groups

and the coagulation function indexes included:prothrombin time（PT）

thrombin time（TT）

activated partial thromboplastin time（APTT） and fibrinogen（FIB）

and D-dimer（D-D） levels.Results The incidence of DTV in the lower extremities of patients in the observation group was 2.78%（2/72）

which was lower than that in the control group of 13.24%（9/68）

and the difference was statistically significant（P<0.05）.The differences were not statistically significant when comparing PT

TT

APTT and FIB and D-D levels in the 2 groups before the intervention（P>0.05）.The levels of PT

TT

APTT and D-D after the intervention were higher in the 2 groups than those before the intervention

and the observation group was higher than the control group

while the levels of FIB were lower in the 2 groups than those before the intervention

with the observation group lower than the control group

and the differences were statistically significant（P<0.05）.Conclusion Evidence-based nursing can effectively prevent the occurrence of lower extremity DVT in patients with cerebral hemorrhage

improve patients’ coagulation function

and promote patients’ recovery

showing significant clinical effects

which is worthy of promotion and application.