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许昌市中心医院SICU
纸质出版日期:2022,
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葛凯杰, 孟佳. 早期与延迟无创呼吸机治疗急性左心衰竭合并Ⅱ型呼吸衰竭的临床效果比较[J]. 保健医学研究与实践, 2022,19(5):39-41.
Ge Kaijie, Meng Jia. Clinical effectiveness of early versus delayed noninvasive ventilator treatment of acute left heart failure combined with type Ⅱ respiratory failure[J]. Health Medicine Research and Practice, 2022,19(5):39-41.
葛凯杰, 孟佳. 早期与延迟无创呼吸机治疗急性左心衰竭合并Ⅱ型呼吸衰竭的临床效果比较[J]. 保健医学研究与实践, 2022,19(5):39-41. DOI:
Ge Kaijie, Meng Jia. Clinical effectiveness of early versus delayed noninvasive ventilator treatment of acute left heart failure combined with type Ⅱ respiratory failure[J]. Health Medicine Research and Practice, 2022,19(5):39-41. DOI:
目的 比较分析早期与延迟无创呼吸机治疗急性左心衰竭合并Ⅱ型呼吸衰竭的临床效果。方法 选取2018年6月—2020年8月河南省某医院收治的120例急性左心衰竭合并Ⅱ型呼吸衰竭患者为研究对象。采用随机数字表法将患者分为早期组及延迟组
各60例。早期组患者在基础治疗的基础上即刻使用无创呼吸机治疗。延迟组患者在基础治疗2 h后
且患者症状未得到缓解时进行无创呼吸机治疗
参数同早期组。比较2组患者治疗前及治疗3 h时心率(HR)、呼吸频率(RR)、氧分压(Pa O2)及平均动脉压(MAP)水平。比较2组患者症状好转时间及住院时间。比较2组患者治疗前及治疗3 h时第1秒用力呼气容积(FEV1)、用力肺活量(FVC)及FEV1/FVC。结果 治疗前
2组患者HR、RR、MAP、Pa O2水平比较
差异无统计学意义(P>0.05)。治疗后
2组患者HR、RR、MAP水平均低于治疗前
且早期组低于延迟组
差异均有统计学意义(P<0.05);而Pa O2水平均高于治疗前
且早期组高于延迟组
差异均有统计学意义(P<0.05)。早期组患者住院时间及症状好转时间均短于延迟组
差异均有统计学意义(P<0.05)。治疗前
2组患者FEV1、FVC、FEV1/FVC水平比较
差异无统计学意义(P>0.05)。治疗后
2组患者FEV1、FVC、FEV1/FVC水平均高于治疗前
且早期组高于延迟组
差异均有统计学意义(P<0.05)。结论 早期进行无创呼吸机治疗急性左心衰竭合并Ⅱ型呼吸衰竭
可有效改善患者临床症状
缩短住院时间及症状好转时间
促进患者康复
值得临床推广应用。
Objective To compare and analyze the clinical effectiveness of early versus delayed noninvasive ventilator treatment of acute left heart failure combined with type Ⅱ respiratory failure.Methods One hundred and twenty patients with acute left heart failure combined with type Ⅱ respiratory failure
admitted to a hospital in Henan Province from June 2018 to August 2020
were selected as subjects and assigned to an early group and a delayed group via the random number table method
with 60 cases in each group.Patients in the early group received early noninvasive ventilators on the basis of basic treatment.Patients in the delayed group received noninvasive ventilators after 2 h of basic treatment when the patients’ symptoms were not relieved
with the same parameters as in the early group.The heart rate(HR)
respiratory rate(RR)
partial pressure of oxygen(Pa O2) and mean arterial pressure(MAP) levels before and at 3 h of treatment were compared between the two groups.The time to symptom improvement and hospitalization time were compared between the two groups.Before treatment and at 3 h of treatment
the forced expiratory volume in1s(FEV1)
forced vital capacity(FVC) and FEV1/FVC were compared between the two groups.Results There was no statistically significant difference in HR
RR
MAP
and Pa O2 levels before treatment between the 2 groups(P>0.05).The levels of HR
RR and MAP in both groups after treatment were lower than those before treatment
and the early group showed lower levels than the delayed group
and the differences were statistically significant(P<0.05);while the Pa O2 was higher than that before treatment
and the early group had higher Pa O2 than the delayed group
and the differences were statistically significant(P<0.05).The duration of hospitalization and the time to symptom improvement were shorter in the early group than those in the delayed group
and the differences were statistically significant(P<0.05).FEV1
FVC
and FEV1/FVC levels before treatment in the 2 groups were compared
and the differences were not statistically significant(P>0.05).FEV1
FVC
and FEV1/FVC levels after treatment were higher in the 2 groups than those before treatment
and the early group was higher than the delayed group
and the differences were statistically significant(P<0.05).Conclusion Early non-invasive ventilator treatment for acute left heart failure combined with type Ⅱ respiratory failure can effectively improve patients’ clinical symptoms
shorten hospitalization time and time to symptom improvement
and promote patients’ recovery
which is worthy of clinical promotion and application.
早期治疗无创呼吸机急性左心衰竭Ⅱ型呼吸衰竭
Early treatmentNon-invasive ventilatorAcute left heart failureType Ⅱ respiratory failure
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