Objective To investigate the diagnostic value of combined fractional exhaled nitric oxide（FeNO）

immunoglobulin E（IgE）

and eosinophil cationic protein（ECP） tests on school-age children with bronchial asthma.Methods One hundred cases of school-age bronchial asthma children admitted to a hospital in Henan province from January to September 2020 were selected as the observation group

and 100 healthy children who underwent physical examination at the hospital during the same period were selected as the control group.The FeNO

IgE

ECP levels and peak expiratory flow as a percentage of the predicted value（PEF%） and the 1 st second forced expiratory volume as a percentage of the predicted value（FEV1%） were compared between the 2 groups.The subjects’ receiver operating characteristic（ROC） curved were also plotted to analyze the efficacy of FeNO

IgE

and ECP in the combined diagnosis of bronchial asthma in school age.Results The levels of FeNO

IgE

and ECP were higher in the study subjects of the observation group than in the control group

and the differences were all statistically significant（P<0.05）.The PEF% and FEV1% of the study subjects in the observation group were lower than those in the control group

and the differences were all statistically significant（P<0.05）.The levels of FeNO

IgE

and ECP were negatively correlated with PEF% and FEV1%

respectively（P<0.05）.The area under the curve（AUC） of FeNO

IgE

and ECP combined to diagnose bronchial asthma in school age was 0.891

and the specificity and sensitivity was 0.974 and 0.785

respectively

which were higher than the values of single test for each index.Conclusion Elevated levels of FeNO

IgE

and ECP are closely related to the occurrence of bronchial asthma in school-aged patients

and negatively correlated with patients’ lung function indexes.The combination of the three tests has high sensitivity and specificity in detecting bronchial asthma in school-aged patients

which can improve the detection rate and thus provide reference for treatment

and therefore

it is worthy of clinical promotion.