Objective：To investigate the prevention measures，knowledge on coronavirus disease 2019（COVID-19） and psychological condition among patients with suspected infection. Methods：Questionnaires about coronavirus prevention measures and knowledge，and symptom self-assessment scale（SCL-90） were used to investigate 65 patients with suspected infection in the isolation ward of West China Hospital，Sichuan University. Results：The score of protective measures was （37.89±6.16），among which higher-score items included：covering nose and mouth when coughing and sneezing（4.58±0.81） and avoiding contact with patients with respiratory diseases（4.57±0.92）；low-score items included：using disinfectants containing alcohol or chlorine to disinfect exposed parts of body and clothes（3.78±0.27），and opening window for ventilation and wiping housewares by using alcohol or chlorine disinfectant（3.85±1.22）. Overall score of knowledge was （15.72±2.82），among which high-score items included：viruses can be transmitted by respiratory droplets（1.00） and the most effective means of prevention and control is early discovery and early isolation（1.00）；low-score items included：mother-to-child transmission（0.29±0.46），blood transmission（0.20±0.40） and infectious disease classifi－cation（0.35±0.48）. Results of SCL-90 scale showed that 15 patients had somatization symptoms（23.1%），19 patients had obsessive-compulsive disorder（29.2%），and 15 patients had interpersonal sensitivity（23.1%）. Scores of somatization，anxiety，fear，neuropathy and sleep disorders were higher than those of domestic norm（P<0.05）. Conclusion：Patients with suspected infection have somatization，anxiety，fear and sleep disorder，therefore，the medical staff should timely take measures for symptoms. In addition，the medical staff should explain protection measures and knowledge for suspected infected person，and promote teaching and announce－ment on right disinfecting ways after going out and transmission ways of COVID-19.