Objective To investigate the clinical efficacy of azelastine hydrochloride nasal spray for the treatment of allergic rhinitis.Method 108 cases of patients with allergic rhinitis were randomly divided into control group and observation group

54 cases in each.The control group was treated with fexofenadine hydrochloride tablets and the observation group were treated with fexofenadine hydrochloride tablets plus azelastine hydrochloride nasal sprays.After 30 days

the effects in two groups were compared.Results The total effective rate in the observation group was 92.6%

slightly higher than the control group of 88.9% and the difference was not statistically significant;the incidence of adverse reactions in the observation was 9.3%

significantly lower than the control group of 25.9%and the difference was statistically significant（P<0.05）.Conclusion Azelastine hydrochloride nasal spray has a significant clinical effect on allergic rhinitis and can reduce the incidence of adverse reactions.It is conducive to the rehabilitation of patients and can improve the quality of their life

worthy of clinical application and promotion.