Objective To probe into the effect of eight-sectioned exercise with manipulation in treating primary dysmenorrhea of female university students.Method 116female university students with primary dysmenorrhea were screened by means of questionnaire and gynecological examination and they were divided randomly into four groups by syndrome differentiation（type of qi stagnation and blood stasis

cold-damp coagulation type and asthenia of qi and blood）

including group treated with eight-sectioned exercise

group treated with manipulation

comprehensive treatment group and control group.These groups were treated for 9weeks

and improvement of dysmenorrhea after the treatment were investigated and diagnosed.Results Diagnostic score and markedly effective rate of patients with dysmenorrhea of three syndrome differentiation after experiment in the comprehensive treatment group were significantly higher than another three groups

and the differences were statistically significant（p<0.05）.Effects of the eight-sectioned exercise in dysmenorrhea of qi stagnation and blood stasis were better than the manipulation;effects of dialectical manipulation in dysmenorrhea patients with asthenia of qi and blood were better than the eight-sectioned exercise

differences between the two groups were statistically significant（p<0.05）.Conclusion Eight-sectioned exercise with manipulation has favorable effects in treating primary dysmenorrhea of female university students.When a single treatment is adopted

the case of patient shall be chosen according to the syndrome differentiation.