Objective To observe the therapeutic effect of kangfuxin rinse solution used on nasopharyngeal carcinoma patients with radiation therapy when the second-degree acute radiodermatitis occurring.Method Experimental group with 23 cases and control group with 23 cases were both treated with exposure therapy.Before medication

the area suffered from radiodermatitis in the experimental group was cleaned with 0.9% physiological saline solution and the infected area was applied with sterile gauze soaked with the physiological saline solution

while the control group only spread mupirocin ointment with aseptic cotton bud.Both groups were treated three times a day: morning

noon and night.Results Total effective rate in the experimental group was 95.65%

in which the effectual rate was 65.22%;Total effective rate in the control group was 78.26%

in which the effectual rate was 30.43%;differences in the effectual rate between the two groups were statistically significant（p<0.05）.Conclusion The therapeutic effect of kangfuxin rinse solution in the treatment of acute radiodermatitis was better than that of the mupirocin ointment.