Objective To explore the relationship between serum high sensitive C-reactive protein（hs-CRP） and coronary heart disease（CHD）

and to analyze if hs-CRP has predictive value for CHD.Method 240 suspected cases of cardiovascular disease received the examination of coronary angiography and the test of serum hs-CRP

and the results were compared and analyzed.Results Three parts 0～<3 mg/L

3～<9 mg/L and ≥9 mg/L after division according to the concentration tested by hs-CRP and their corresponding detection rates of CHD were 54.17%

63.79% and 70.97% respectively.The difference between 3～<9 mg/L and 0～<3 mg/L was of detection significance（χ2=4.80

P<0.05）.The abnormal rate of hs-CRP in patients with CHD was 55.48%

and non-CHD patients 41.49% and the difference was statistically significant（χ2=4.48

P<0.05）.The difference between 3～<9 mg/L and 0～<3 mg/L or ≥9 mg/L was not statistically significant（P>0.05）.Conclusion Serum hs-CRP is a risk factor of CHD and is closely related to the occurrence

development and predictability of CHD.It can be used as the monitoring index of early diagnosis and condition of CHD

worthy of certain clinical promotion.