Objective To observe the clinical effect and safety of qingkailing injecta on children’s acute upper respiratory infection.Method The child patients were randomly divided into the experimental group

48 cases treated with qingkailing injecta 0.8 mL/（kg·d）

and the control group

47 cases treated with bingduzuo injecta 10～15 mg/（kg·d）

once a day

3～5 days for a period.Besides this

the two groups received the same symptomatic threatment.Results The total effective rate is 97.92% in experimental group and 72.34% in the control group （P<0.01）.There were no adverse reactions in two groups.Conclusion Qingkailing injecta is safe and effective on children’s acute upper respiratory infection

with no adverse reactions

having superiority over bingduzuo injecta.