The basic medicine teaching must meet the clinical application， while the clinical practice should be timely feedback to basic medical teaching， which is the embodiment of the idea in the translational medicine. The experimental teaching is an important part of modern pathology teach ing. We actively improve the experiment course and deepen the basic concept of translational medicine in the medical education development by adopting such approaches as using the problem based learning method（PBL） to promote the link between basic courses and clinical pathology， integrating and optimizing the teaching content to promote the knowledge mastery and conducting molecular pathology research to promote the implementation of translational medicine.