THE EFFECTS OF TUMOR VACCINE IMMUNIZATION ON THE GROWTH OF THE TRANSPLATABLE SPONTANEOUS HEPATOMA OF 615 INBRID MICE (H615)

Department of Pathophysiology Liu YunKang Yu MaoTang

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THE EFFECTS OF TUMOR VACCINE IMMUNIZATION ON THE GROWTH OF THE TRANSPLATABLE SPONTANEOUS HEPATOMA OF 615 INBRID MICE (H615)

更新时间：2024-01-17

- THE EFFECTS OF TUMOR VACCINE IMMUNIZATION ON THE GROWTH OF THE TRANSPLATABLE SPONTANEOUS HEPATOMA OF 615 INBRID MICE (H615)
- Journal of Chongqing Medical University Issue 3, Pages: 174-178(1985)
- 作者机构：
  
  重庆医学院病理生理教研室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1985，
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[1]刘运康,余懋棠.瘤苗免疫对615小鼠可移植性肝癌生长的影响[J].重庆医学院学报,1985(03):174-178.

Department of Pathophysiology Liu YunKang Yu MaoTang. THE EFFECTS OF TUMOR VACCINE IMMUNIZATION ON THE GROWTH OF THE TRANSPLATABLE SPONTANEOUS HEPATOMA OF 615 INBRID MICE (H615). [J]. Journal of Chongqing Medical University (3):174-178(1985)
[1]刘运康,余懋棠.瘤苗免疫对615小鼠可移植性肝癌生长的影响[J].重庆医学院学报,1985(03):174-178. DOI：

Department of Pathophysiology Liu YunKang Yu MaoTang. THE EFFECTS OF TUMOR VACCINE IMMUNIZATION ON THE GROWTH OF THE TRANSPLATABLE SPONTANEOUS HEPATOMA OF 615 INBRID MICE (H615). [J]. Journal of Chongqing Medical University (3):174-178(1985) DOI：

摘要

615小鼠经H615瘤块移植致敏后并不能抵御相同肿瘤的接种攻击

亦无存活时间延长的现象。用H615组织匀浆免疫的小鼠接种肿瘤后

肿瘤生长加速;60天处死时平均肿瘤重量较对照组明显增加（P<0.05）

发癌率也由对照组的80%增至100%（P>0.05）。但同时接受上述处理的小鼠却没有明显的肿瘤促进作用

文内对此进行了讨论。实验结果显示主动免疫不能抑制肿瘤的生长

反而有促进肿瘤生长的可能。

Abstract

615 mice

sensitized with living H615 cells

did not acqure the resistance to the challenge of same tumor and their mean survival was not longer than the controls’anymore. Pretreatment with H615 tissue homogenate even enhanced the growth of the ?implants of the tumor. At 60 days

the mean weight of the tumor transplatated co-nsiderablly increased than that of the controls (P<C0.05). Meanwhile

tumor incidence of this group went up from 80% of the controls to 100% (P>0.05). But for the others who received both of the treatment above

the more rapidly developing tumor had not been found. The possible reasons of this are discussed.The overall conclusion from this study was that the active immunizations enhanced rather than inhibited tumor growth.

关键词

615小鼠肿瘤主动免疫移植性肝癌免疫促进作用

Keywords

615 miceTumor active immunizationTransplatable hepatomaImmunological enhancement

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