Objective: comprehending urine trace protein detect significance to detect earlier period kidnry impaired in systemic lupus erythematosus patien of urine protein determined negative.Method: employing ELISH technique assay urine α1-microglobulin and urine trace albumin and transferring and urine IgG in 27 systemic lupus erythematosus patien and 30 health.Produce: patien and paired normal subjects comparison : urine α1-microglobulin and urine trace albumin and transferring and urine IgG were higher in patien bundle(P<0.002
P<0.004
P<0.001
P<0.01);and in active phase(P<0.01
P<0.02
P<0.02
P<0.03)
which were significantly higher.Conclusion: α1-microglobulin and urine trace albumin and transferring and urine IgG may to become earlier period kidney lesion marker in systemic lupus erythematosus.