Objective: To study the clinical types

morbidity

relationships between episode and pregnant weeks

laboratory examinations and the influences to the perinatal and maternal

and to discuss the possibile mechanisms of hepatopathy in 71 pregnancies.Methods: The data of 71 pregnancies with hepatopathy admitted in Chongqing University of Medical Science from 2002 to 2004 were reviewed

and the clinical types

morbidity

relationships between episode and pregnant weeks

mechanisms

laboratory examinations

influences to the perinatal and maternal were explored.Results: There were 53 cases of viral hepatitis of pregnancy(VHP)

6 of intracholestasis of pregnancy(ICP)

3 of acute fatty liver of pregnancy(AFLP) in the group.The degree of liver injury was accordant to that of hepatitis.All ICP cases developed in the third trimester.AFLP developed all in the third trimester.The case of HELLP syndrome developed in 37 weeks of pregnancy with liver function disorder and recovered soon after birth.Conclusions: VHP

ICP and AFLP are the most common types of hepatopathy of pregnancy.Hepatitis B is common to see in VHP.They can happen in each trimester of pregnancy but the third trimester does more.ICP often develops in the third trimester of pregnancy with obvious inflammation of hepatocytes but no obvious jaundice

while congestion exists.No obvious influence to the perinatal or the maternal is seen.AFLP often develops in the third trimester of pregnancy with sudden episode

rapid progress and fulminant hepatic injury which can cause severe results to the maternal and perinatal.HELLP syndrome develops in the third trimester of pregnancy mostly with massive injure to the liver

and recovered soon after birth.It can influence the perinatal obviously.