An empirical study of mongolian gazelle muscle exposed to MRI guided high intensity focused ultrasound

DONG Jie; et al

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An empirical study of mongolian gazelle muscle exposed to MRI guided high intensity focused ultrasound

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- An empirical study of mongolian gazelle muscle exposed to MRI guided high intensity focused ultrasound
- Journal of Chongqing Medical University Issue 9, Pages: 1099-1102(2008)
- 作者机构：
  
  1. 重庆医科大学医学超声工程研究所
  2. 重庆医科大学附属第二医院妇产科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R310
- Published：2008，
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[1]董洁,熊正爱,王智彪,张炼,刘映江,胡晓.磁共振成像实时监控高强度聚焦超声热消融羊肌肉组织的可行性研究[J].重庆医科大学学报,2008(09):1099-1102.

DONG Jie, et al. An empirical study of mongolian gazelle muscle exposed to MRI guided high intensity focused ultrasound. [J]. Journal of Chongqing Medical University (9):1099-1102(2008)
[1]董洁,熊正爱,王智彪,张炼,刘映江,胡晓.磁共振成像实时监控高强度聚焦超声热消融羊肌肉组织的可行性研究[J].重庆医科大学学报,2008(09):1099-1102. DOI：

DONG Jie, et al. An empirical study of mongolian gazelle muscle exposed to MRI guided high intensity focused ultrasound. [J]. Journal of Chongqing Medical University (9):1099-1102(2008) DOI：

摘要

目的:探讨磁共振成像（Magnetic Resonance Imaging

MRI）温度图（Temperature-Map

T-Map）监控高强度聚焦超声（High intensity focused ultrasound

HIFU）热消融活体动物的可行性。方法:对10只活体南疆黄羊大腿肌肉行体外定点HIFU辐照

辐照过程中以MRI T-Map监控靶区温度变化

比较T-Map与组织实际损伤区域的一致性。结果:磁共振导航HIFU治疗系统热消融正常羊大腿肌肉组织

形成肉眼可见的损伤。T-Map在辐照过程中温度呈现逐渐升高至辐照结束即刻达峰值后又逐渐下降的规律变化

且辐照结束即刻图中红色范围（60℃～110℃）与实际组织损伤范围一致（P>0.05）。结论:初步验证了MRI T-Map监控HIFU热消融活体动物肌肉组织是可行的。

Abstract

Objective:To explore the feasibility of the treatment system of Magnetic resonance imaging guided high intensity focused ultrasound. Methods:MR Imaging guided HIFU thermocoagulation was carried out in muscular tissues of southern xinjiang mongolian gazelle.The target tissues’ histological changes were examined in comparison with normal.Meanwhile

the relationship between the adscendent temperature in T-Map and practical necrosis was compared. Results:Macroscopic damages could be made in normal goat leg muscular tissue.During HIFU

T-Map showed a dynamic regularity

and the temperature of focus went up expeditiously.At the end of the treatment

the temperature reached its peak value.Immediately

it descended to foundational temperature fleetly. And just at the end of treatment

a correlation existed between red region(60℃～110℃)and tissue necrosis(P>0.05). Conclusion:The treatment system of MR Imaging guided HIFU is feasible and effective.

关键词

高强度聚焦超声磁共振成像温度图

Keywords

HIFUMRITemperature-Map

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