Association between Sp110 gene and susceptibility to tuberculosis

XIONG Yu; et al

您当前的位置：

首页 >

文章列表页 >

Association between Sp110 gene and susceptibility to tuberculosis

更新时间：2024-01-17

- Association between Sp110 gene and susceptibility to tuberculosis
- Journal of Chongqing Medical University Issue 4, Pages: 423-427(2008)
- 作者机构：
  
  1. 重庆医科大学公共卫生学院流行病学教研室
  2. 重庆医科大学公共卫生学院流行病学教研室,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R521
- Published：2008，
扫描看全文
[1]熊宇,周丹,陶杨,李革.Sp110基因与肺结核易感相关性研究[J].重庆医科大学学报,2008(04):423-427.

XIONG Yu, et al. Association between Sp110 gene and susceptibility to tuberculosis. [J]. Journal of Chongqing Medical University (4):423-427(2008)
[1]熊宇,周丹,陶杨,李革.Sp110基因与肺结核易感相关性研究[J].重庆医科大学学报,2008(04):423-427. DOI：

XIONG Yu, et al. Association between Sp110 gene and susceptibility to tuberculosis. [J]. Journal of Chongqing Medical University (4):423-427(2008) DOI：

摘要

目的:研究Sp110基因rs1135791r、s722555r、s116799831r、s3948464位点基因多态性与重庆市汉族人群肺结核发病的关系。方法:采用病例对照研究设计

检测rs1135791r、s722555r、s116799831r、s3948464位点SNP多态性

用SAS软件进行显著性检验。结果:（1）Sp110基因rs1135791 CT基因型r、s722555 GG基因型r、s116799831 GG基因型r、s3948464 CC基因型在病例组的频率明显高于对照组;（2）病例组rs1135791 C等位基因r、s722555 G等位基因r、s116799831 G等位基因r、s3948464C等位基因频率都高于对照组

差异有统计学意义。结论:rs1135791 C/Tr、s722555 A/Gr、s116799831 A/Gr、s3948464 C/T可能是重庆市汉族人群肺结核易患的危险因素。

Abstract

Objective:To study the association between rs1135791、rs722555、rs116799831、rs3948464 polymorphisms of Sp110 gene and susceptibility to tuberculosis of Han people in Chongqing.Methods:Using case-control study

rs1135791、rs722555、rs116799831、rs3948464 polymorphisms of Sp110 gene were detected.The test of significance was performed with the computer program

SAS Version 8.2.Results:(1)The frequencies of rs1135791 CT、rs722555 GG、rs116799831 GG、rs3948464 CC had statistically significant difference between the case and the control group.(2)The frequencies of rs1135791 C allele、rs722555 G allele、rs116799831 G allele、rs3948464 C allele had statistically significant difference between the case and the control group.Conclusion:The rs1135791 C/T、rs722555 A/G、rs116799831 A/G、rs3948464 C/T polymorphisms of Sp110 gene were possibly susceptible to the tuberculosis of the Han people in Chongqing.

关键词

Sp110基因肺结核

Keywords

Sp110 geneTuberculosis

references

Views

144

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

A Spatio-Temporal analysis of tuberculosis incidence and regional per capita GDP in Chongqing,2011-2014

Related Author

Que Ping

Xu Xiaolan

Wen Xiaoyan

Xu Feilong

Sun Anlong

Peng Bin

Related Institution

Teaching and Research Section of Health Statistics and Information Management,Collaborative Innovation Center of Social Risks Governance in Health,School of Public Health and Management,Chongqing Medical University

Chongqing Health Information Center

Department of Quality Control and Evaluation,The Third People’s Hospital of Chengdu

⁰