Objective:Searching after the regularity of the expressions the insulin-like growth factors(IGF-1) inside the neonatal rabbits with chronic intrauterine anoxemia give to brain Tissues and serums. Methods: Choosing 24 Zelanian rabbits that have been in afternoon pregnancy

we divide them into three stochastic contratest group by chance: the control group

the anoxic group and the group interfered with Chinese traditional medicine. Then we contrast the expressions and changes of these groups with IGF-1 in brain tissues and in serums. Results: Contrasting IGF-1 in brain tissues

checked up with χ2. In three different groups

we have found that the differences of their expressions have some statistical significance (P <0.01);IGF-1 in brain tissues of the anoxic group is higher than the group interfered with Chinese traditional medicine and IGF-1 in brain tissues of the group interfered with Chinese traditional medicine is higher than the control group.Determined the contents of IGF-1 in serums on rabbits by ELISA

the contents of IGF-1 in serums of the anoxic group is extremely remarkably lower than the control group(P <0.01)

while the contents of IGF-1 in serums of the group interfered with Chinese traditional medicine is extremely remarkably lower than the anoxic group.Conclusion:In this article

there occurs the mentions: IGF-1 has been redistributed in the bodies of HIE neonatal rabbits;Irritable reactions inside brain tissues have been brought into existance in order to protect nerve cells

then IGF-1 from the periislet extro-blood all assembled into the central nervous system

then participate in the intrinsic protection mechanism.