Risk factors analysis of secondary pulmonary fungal infections related to ventilator associated pneumonia

HUANG Yu-hui; TAN Hui; ZHU Da-qing; LI Zhi-guan; HE Bing-wen

您当前的位置：

首页 >

文章列表页 >

Risk factors analysis of secondary pulmonary fungal infections related to ventilator associated pneumonia

更新时间：2024-01-17

- Risk factors analysis of secondary pulmonary fungal infections related to ventilator associated pneumonia
- Journal of Chongqing Medical University Vol. 36, Issue 12, Pages: 1488-1491(2011)
- 作者机构：
  
  湖南省郴州市第一人民医院呼吸内科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R563.1
- Published：2011，
扫描看全文
[1]黄玉晖,谭辉,朱大庆,李炽观,何炳文.呼吸机相关性肺炎继发肺真菌感染的危险因素分析[J].重庆医科大学学报,2011,36(12):1488-1491.

HUANG Yu-hui, TAN Hui, ZHU Da-qing, et al. Risk factors analysis of secondary pulmonary fungal infections related to ventilator associated pneumonia. [J]. Journal of Chongqing Medical University 36(12):1488-1491(2011)
[1]黄玉晖,谭辉,朱大庆,李炽观,何炳文.呼吸机相关性肺炎继发肺真菌感染的危险因素分析[J].重庆医科大学学报,2011,36(12):1488-1491. DOI：

HUANG Yu-hui, TAN Hui, ZHU Da-qing, et al. Risk factors analysis of secondary pulmonary fungal infections related to ventilator associated pneumonia. [J]. Journal of Chongqing Medical University 36(12):1488-1491(2011) DOI：

摘要

目的:探讨呼吸机相关性肺炎（Ventilator associated pneumonia

VAP）继发真菌感染的有关危险因素

为临床早期诊断及治疗提供参考依据。方法:回顾性收集本院呼吸内科2005年6月-2010年6月期间经临床确诊为VAP的126例患者的临床资料

根据是否继发肺真菌感染分为真菌感染组（56例）和非真菌感染组（70例）

分别对性别、年龄、合并基础疾病、血糖、低蛋白血症、气管切开、深静脉置管、机械通气时间、放疗或化疗、抗生素使用时间、联合应用抗生素、激素（或免疫抑制剂）、APACHEⅡ评分等13项危险因素进行单因素分析

并对显著相关性危险因素进行Logistic回归分析。结果:单因素分析显示年龄、合并基础疾病、血糖、低蛋白血症、机械通气时间、放疗或化疗、抗生素使用时间、联合应用抗生素、激素（或免疫抑制剂）、APACHEⅡ评分呈显著相关性;Logistic回归分析提示年龄、血糖、机械通气时间、放疗或化疗、抗生素使用时间、联合应用抗生素、激素（或免疫抑制剂）、APACHEⅡ评分与继发肺部真菌感染呈显著相关性。结论:VAP真菌感染受多种因素影响

临床治疗时应具体分析

对于高龄、机械通气时间长、血糖控制差、联合使用抗生素及时间长、激素（或免疫抑制剂）、APACHEⅡ评分等提示存在继发真菌敏感危险因素的

应重视这些危险因素的预测价值。

Abstract

Objective:To explore the risk factors for secondary pulmonary fungal infections related to ventilator associated pneumonia(VAP) in order to provide the reference for clinical diagnosis and treatment.Methods:The clinical data of 126 patients with pulmonary fungal infections related to VAP from June 2005 to June 2010 were retrospectively collected.The patients were divided into fungal infection group(56 patients) and non-fungal infection group(70 patients).The risk factors including gender

age

complicated basic diseases

blood sugar

hypoalbuminemia

trachea incision

deep venipuncture

mechanical ventilation time

radiation or chemotherapy

time of using antibiotics

combined use of antibiotics

glucocorticosteroid(immunodepressant)

and APACHEⅡscore were analyzed using the single factor analysis and logistic regression.Results:The single factor analysis showed that age

complicated basic diseases

blood sugar

hypoalbuminemia

mechanical ventilation time

radiation and chemotherapy

time of using antibiotics

combined use of antibiotics

glucocorticosteroid(immunodepressant)

and APACHEⅡscore were significantly correlated.Logistic regression analysis suggested blood sugar

mechanical ventilation time

time of using antibiotics

combined use of antibiotics

glucocorticosteroid(immunodepressant)

and APACHEⅡscore were significantly correlated.Conclusion:Multiple factors affect pulmonary fungus infection

and clinical treatment should be specificly analysed as to the risk factors of older age

mechanical ventilation time

blood sugar

time of using antibiotics

combined of antibiotics

glucocorticosteroid(immunodepressant)

and high APACHEⅡscore.

关键词

呼吸机相关性肺炎真菌感染危险因素

Keywords

ventilator associated pneumoniafungal infectionrisk factors

references

Views

154

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Monitoring and interventions for ventilator associated pneumonia in neurological intensive care unit

Risk factors of contrast-induced nephropathy in patients with diabetes after percutaneous coronary intervention and its prognosis

Clinical distribution characteristics and analysis on risk factors of extracranial carotid artery stenosis in patients with acute ischemic stroke

Correlation between the cardio-ankle vascular index and cardiovascular risk factors in health examination population

Prevalence and risk factors of impaired fasting glucose among physical examination population in the western new city of Chongqing

Related Author

Xing Feng

Liu Guangwei

Mei Chang

Liu Juan

Zhang Shanwen

Qu Xiaolong

Meng Jing

Hu Houyuan

Related Institution

Department of Neurology，The First Affiliated Hospital of Chongqing Medical University

Department of Cardiology,the First Affiliated Hospital of Third Military Medical University

Department of Neurology,the Second Hospital of Lanzhou University

Department of Cardiovascular Medicine,The First Affiliated Hospital of Chongqing Medical University

Department of Nursing,The First Affiliated Hospital of Chongqing Medical University

⁰