Objective:To analyze the high-flux hemodialysis in diabetic renal failure patients with inflammatory mediators

insulin resistance and blood lipids

etc.

and to explore its clinical application.Methods:40 cases of diabetic renal failure patients

20 cases of high-flux hemodialysis

20 cases of conventional low-flux hemodialysis

6 months after treatment were compared indicators of inflammatory mediators

insulin resistance index and serum lipid level changes.Results:After treatment

serum creatinine levels were significantly decreased(P<0.01);high-flux dialysis group after treatment

levels of inflammatory mediators

insulin resistance index and serum lipid levels decreased significantly compared with before treatment(P<0.05

P<0.01)

In addition to the conventional dialysis group total cholesterol

apolipoprotein B and some other blood lipid levels than before treatment(P<0.05)

the remaining indicators did not change significantly(P>0.05).Conclusion:applied to high-flux hemodialysis in patients with diabetic kidney failure

which can effectively remove the large molecules of inflammatory mediators

reduce the micro-inflammatory state

insulin resistance and to correct abnormal lipid metabolism

thus controlling the development of diabetic nephropathy and reduce cardiovascular complications occurred

to improve the prognosis

is worthy of clinical application.