Seroepidemiological study of epstein-barr virus infection in children under 12 years old

WANG Yang; XU Hong-mei

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Seroepidemiological study of epstein-barr virus infection in children under 12 years old

更新时间：2024-01-17

- Seroepidemiological study of epstein-barr virus infection in children under 12 years old
- Journal of Chongqing Medical University Vol. 36, Issue 12, Pages: 1510-1512(2011)
- 作者机构：
  
  重庆医科大学附属儿童医院感染消化科儿童发育疾病研究省部共建教育部重点实验室儿科学重庆市重点实验室重庆市儿童发育重大疾病诊治与预防国际科技合作基地
- 作者简介：
- 基金信息：
- DOI：
  CLC： R733.1;R181.3
- Published：2011，
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[1]汪洋,许红梅.12岁以下儿童EB病毒感染的血清流行病学调查[J].重庆医科大学学报,2011,36(12):1510-1512.

WANG Yang, XU Hong-mei. Seroepidemiological study of epstein-barr virus infection in children under 12 years old. [J]. Journal of Chongqing Medical University 36(12):1510-1512(2011)
[1]汪洋,许红梅.12岁以下儿童EB病毒感染的血清流行病学调查[J].重庆医科大学学报,2011,36(12):1510-1512. DOI：

WANG Yang, XU Hong-mei. Seroepidemiological study of epstein-barr virus infection in children under 12 years old. [J]. Journal of Chongqing Medical University 36(12):1510-1512(2011) DOI：

摘要

目的:了解12岁以下儿童EB病毒（Epstein-barr virus

EBV）感染现状及流行病学特点。方法:收集2010年重庆儿童医院539份0

2岁儿童的血清标本

采用ELISA法

对每份血清进行EBVCA-IgG及EBVCA-IgM检测

根据检测结果判断血清标本是否存在EBV感染。Excel软件储存数据

运用统计学分析软件SPSS17.0进行统计分析。结果:重庆地区12岁以下儿童EBV新发感染率为9.7%

累计感染率为51.2%。0岁

、

0.5岁

、

1岁

、

3岁

及

2岁新发感染率分别为20.0%、8.2%、12.4%、4.9%、7.0%;累计感染率分别为70.9%（由于胎传抗体的影响

实际感染率低于该值）、17.6%、33.1%、57.4%、71.6%。结论:重庆地区12岁以下儿童EBV的感染率低于目前公认的我国3

岁儿童的感染率（90%）;也低于2006年北京地区3岁以下儿童的感染率（71%）

但仍高于经济发达的西方国家

EBV感染的高峰年龄段在学龄前期。

Abstract

Objective:To understand epstein-barr virus(EBV) infection status and epidemiological characteristics in children under 12 years old in Chongqing.Methods:539 serum samples of healthy children of 0~12 years old were collected from the Children’s Hospital of Chongqing Medical University.EBVCA-IgG and EBVCA-IgM in each sample were tested by ELISA.The database was established with Excel and statistical analysis was performed with software SPSS17.0.Results:The cumulative infection rate of EBV in children between 0~12 years old was 51.2% and recent infection rate was 9.7%.The recent infection rate of EBV in 0 year~

0.5 year~

1 year~

3 years~ and 6~12 years group was 20%

8.2%

12.4%

4.9% and 7.0%

respectively.The cumulative infection rate in 0 year~

0.5 year~

1 years~

3 years~ and 6~12 years group was 70.9%

17.6%

33.1%

57.4% and 71.6%

respectively.Conclusion:EBV infection rate in children under 12 years in Chongqing is lower than 90%

the currently reported rate of EBV infection in children between 3~5 years old in China

and also lower than that in children under 3 years old in Beijing in 2006.However

it is still above the rate in western economically developed countries.Pre-school age is the peak period for EBV infection.

关键词

EB病毒儿童流行病学衣壳抗原

Keywords

Epstein-Barr viruschildseroepidemiologycapsid antigen

references

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Department of Pediatric Endocrinology，Genetics，and Metabolism，The Affiliated Women’s and Children’s Hospital，School of Medicine，University of Electronic Science and Technology of China · Chengdu Women’s and Children’s Central Hospital

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