Research progress on the protective mechanism of remote limb ischemic post-condictioning on cerebral ischemia reperfusion injury

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Research progress on the protective mechanism of remote limb ischemic post-condictioning on cerebral ischemia reperfusion injury

更新时间：2022-06-24

- Research progress on the protective mechanism of remote limb ischemic post-condictioning on cerebral ischemia reperfusion injury
- null Issue 10, Pages: 907(2021)
- 作者机构：
  
  1. 赣南医学院,江西,赣州,341000
  2. 赣南医学院第一附属医院麻醉手术中心,江西,赣州,341000
- 作者简介：
- 基金信息：
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Research progress on the protective mechanism of remote limb ischemic post-condictioning on cerebral ischemia reperfusion injury. [J]. null (10):907(2021)
DOI：

Research progress on the protective mechanism of remote limb ischemic post-condictioning on cerebral ischemia reperfusion injury. [J]. null (10):907(2021) DOI：

摘要

缺血性脑卒中是危害人类健康的常见病、多发病，因其高发病率、高致残率和高病死率，给家庭、社会带来沉重的负担。脑组织经过一定时间的缺血后，再次恢复血液灌注时，其功能及结构损伤反而会加重，即脑缺血再灌注（I/R）损伤。目前有研究表明肢体远端缺血后处理（RIPostC）对I/R损伤后的脑组织具有内源性神经保护作用。大量的基础研究及临床研究显示，RIPostC对减轻I/R损伤和改善预后有重要作用。RIPostC主要通过神经、体液、免疫等多种途径在脑梗死发病过程的多个环节中发挥脑保护作用，但其确切机制尚不明确。本文就RIPostC脑保护机制的研究进展作一综述，旨在为RIPostC的临床转化及进一步的机制研究提供一定的参考。

Abstract

关键词

缺血性脑卒中脑缺血再灌注损伤肢体远端缺血后处理脑保护研究进展

Keywords

ischemic strokecerebral ischemia reperfusion injuryremote limb ischemic post-conditioningcerebral protectionresearch progress

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