Objective:To investigate the clinical effect of the Qi-tonifying

pathogenic wind-dispelling

and collateral-dredging method（Zhilong Huoxue Tongyu capsules）in the treatment of patients with chronic heart failure（CHF）with Qi deficiency and blood stasis and its effect on myocardial remodeling.Methods:A total of 40 CHF patients with Qi deficiency and blood stasis who met the inclusion criteria were randomly divided into conventional treatment group and Zhilong treatment group

with 20 patients in each group.After 6 months of treatment

cardiac magnetic resonance imaging was used to measure myocardial extracellular volume fraction to reflect the degree of myocardial fibrosis

and the two groups were compared in terms of left ventricular ejection fraction

left ventricular end-diastolic diameter

N-terminal pro-brain natriuretic peptide

6-minute walking test results

and traditional Chinese medicine（TCM）symptoms of Qi deficiency and blood stasis before and after treatment.The condition of CHF and the outcome of TCM symptoms were comprehensively evaluated.Results:After 6 months of treatment

both groups had varying degrees of improvements in left ventricular ejection fraction

left ventricular end-diastolic diameter

N-terminal pro-brain natriuretic peptide

and 6-minute walk test results

and the Zhilong treatment group had significantly better improvements than the conventional treatment group（P < 0.05）.After treatment

compared with the conventional treatment group

the Zhilong treatment group had a significantly lower myocardial extracellular volume fraction measured by cardiac magnetic resonance imaging（P < 0.01）and a significantly better improvement in the symptoms of Qi deficiency and blood stasis（P < 0.01）.Conclusion:Compared with the conventional treatment group

the Zhilong treatment group has obvious advantages in improving the symptoms of Qi deficiency and blood stasis

left ventricular ejection fraction

6-minute walk test results

ventricular end-diastolic diameter

N-terminal pro-brain natriuretic peptide

and myocardial extracellular volume fraction

suggesting that Zhilong Huoxue Tongyu capsules（the Qi-tonifying

pathogenic wind-dispelling

and collateral-dredging method）can achieve the above effect by inhibiting myocardial fibrosis and delaying myocardial remodeling.