Objective To investigate the role of electrocardiograph（ECG）in predicting response to cardiac resynchronization therapy（CRT）.Methods Ninety-four patients diagnosed with congestive heart failure who underwent CRT at a hospital in Chongqing between January 2014 and December 2016 were included in this study.Based upon patient response to CRT 12 months after CRT

these patients were classified into the responsive group（n=47）and the unresponsive group（n=47）.The correlation between patient response to CRT and the following variables were assessed:gender

age

comorbidities（hypertension

diabetes

ventricular arrhythmia

ischemic cardiomyopathy

and complete left bundle branch block[CLBBB]）

as well as QRS duration

QTc interval and Tpe interval before and 24 hafter CRT.Results The age

gender composition

and proportions of patients with concomitant hypertension

diabetes

ventricular arrhythmia

ischemic cardiomyopathy

and CLBBB before CRT were comparable between the two groups（P>0.05）.At 24 hafter CRT

the QRS duration

QTc interval and Tpe interval in the responsive group were shorter than those before CRT in the same group

also shorter than those observed in the unresponsive group（P<0.05）.The QRS duration

QTc interval and Tpe interval in the unresponsive group were similar before and 24 hafter CRT（P>0.05）.Multivariable Logistic regression analysis showed that

both substantial shortening of QTc interval after CRT and substantial shortening of Tpe interval 24 hafter CRT were independent predictors of patient response to CRT（P<0.05）.Conclusion ECG is of great value in predicting response to CRT;substantial shortening of QTc interval and Tpe interval 24 hafter CRT were both independent predictors of patient response to CRT.