Analysis of 5 years accumulative survival of patients with acute coronary syndrome

Shi Liya; Ding Junxia; Li Jun; Lei Yajun; Xie Kangsheng

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Analysis of 5 years accumulative survival of patients with acute coronary syndrome

更新时间：2021-08-23

- Analysis of 5 years accumulative survival of patients with acute coronary syndrome
- Health Medicine Research and Practice Vol. 14, Issue 3, Pages: 42-45(2017)
- 作者机构：
  
  平煤集团十矿医院内科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R541.4
- Published：2017，
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[1]史利亚,丁军侠,李军,雷亚军,谢康生.急性冠状动脉综合征患者5年累积存活率的影响因素分析[J].保健医学研究与实践,2017,14(03):42-45+48.

Shi Liya, Ding Junxia, Li Jun, et al. Analysis of 5 years accumulative survival of patients with acute coronary syndrome. [J]. Health Medicine Research and Practice 14(3):42-45(2017)
[1]史利亚,丁军侠,李军,雷亚军,谢康生.急性冠状动脉综合征患者5年累积存活率的影响因素分析[J].保健医学研究与实践,2017,14(03):42-45+48. DOI：

Shi Liya, Ding Junxia, Li Jun, et al. Analysis of 5 years accumulative survival of patients with acute coronary syndrome. [J]. Health Medicine Research and Practice 14(3):42-45(2017) DOI：

摘要

目的探讨急性冠状动脉综合征（ACS）患者5年累积存活率的影响因素。方法选取平顶山市某医院心内科收治的285例ACS患者为研究对象

入院时统计患者性别、年龄、体质量指数（BMI）、高血压史、糖尿病史、吸烟史、心源性休克史、冠心病家族史等信息

并于入院24h内检测患者血清高敏C反应蛋白（hsCRP）

空腹血糖（FBG）

肌酐（SCr）

甘油三酯（TG）

总胆固醇（TC）

低密度脂蛋白胆固醇（LDL-C）

高密度脂蛋白胆固醇（HDL-C）水平

患者出院后

记录其存活时间

分析影响其累积存活率的因素。结果截止到随访日

失访及因其他因素死亡19例

心血管性死亡82例

存活184例

累积存活率为70.1%。单因素Cox比例风险分析结果表明

患者5年累积存活率的影响因素有年龄

糖尿病史

吸烟史

冠心病家族史

并发左室功能不全（LVF）、心源性休克、心室颤动

hs-CRP≥10.0mg/L

SCr≥120μmol/L（P

0.05）;多因素Cox比例风险分析结果表明

患者5年累积存活率的影响因素有年龄

hs-CRP≥10.0 mg/L和SCr≥120μmol/L（P

0.05）。hs-CRP

10.0mg/L和hs-CRP≥10.0mg/L患者的5年累积存活率比较

差异有统计学意义（χ

=14.076

0.01）;SCr

120μmol/L和SCr≥120μmol/L患者的5年累积存活率比较

差异有统计学意义（χ

=11.548

0.01）;年龄6170岁和年龄≥70岁患者的5年累积存活率与年龄≤50岁的患者比较

差异有统计学意义（χ

=7.602

19.842;P

0.01）。结论 hs-CRP

SCr水平和年龄是影响ACS患者5年累积存活率的主要因素

临床上可采取有效措施及时监测并控制ACS患者hs-CRP和SCr水平

此举对改善患者预后

降低病死率有重要意义。

Abstract

Objective To study the factors influencing 5years cumulative survival of patients with acute coronary syndrome（ACS）.Methods 285 patients with ACS from a hospital in Pingdingshan city were selected as research objects

and on admission patients′gender

age

body mass index（BMI）

hypertension history

diabetes mellitus

smoking history

family history of coronary heart disease

cardiac shock were recorded.After being admitted to hospital within 24hpatients′serum in which high-sensitivity c-reactive protein（hsCRP）

fasting blood glucose（FBG）

creatinine（SCr）

triglyceride（TG）

total cholesterol（TC）

low-density lipoprotein cholesterol（LDL-C）

high density lipoprotein cholesterol（HDL-C）levels were detected;after discharge the patient′s survival time were recorded and the influencing factors of the 5years cumulative survival for patients were analyzed.Results By the end of the follow-up the cumulative survival was 70.1%（19cases lost to follow-up and died of other factors

82 cases died of heart vascular disease and 184 cases survived）.Single factor Cox proportional hazards analysis results showed that the factors influencing 5years cumulative survival of patients included age

history of diabetes

smoking history

family history of coronary heart disease

complication of left ventricular dysfunction（LVF）

complication of cardiac shock

complication of ventricular fibrillation

hs-CRP≥10.0mg/L

SCr≥120μmol/L（P

0.05）;Multiariable Cox proportional hazards analysis results showed that the influence factors of 5years cumulative survivalwere age

the hsCRP≥10.0mg/L

SCr≥120μmol/L（P

0.05）.Comparing the 5years cumulative survival of patients whose hs-CRP

10.0mg/L and hs-CRP≥10.0mg/L

the difference was statistically significant（χ

=14.076

0.01）;in the comparsion between that of patients whose SCr

120μmol/L and SCr≥120μmol/L

the difference was statistically significant（χ

=11.548

0.01）;in the comparison between patients aged 61 to 70with patients aged 70 and older

the difference was statistically significant（χ

=7.602

19.842;P

0.01）.Conclusion hs-CRP

SCr levels and age are the main factors influencing the cumulative survival（5years）of patients with ACS and effective measures could be taken to monitor and control the levels of hs-CRP

SCr which is meaningful for improving the prognosis of patients and reduce mortality.

关键词

急性冠状动脉综合征预后影响因素累积存活率

Keywords

Acute coronary syndromePrognosisinfluencing factorsAccumulative survival

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