[1]刘新伟,Dr. A Karu.罗哌卡因与罗哌卡因复合可乐定行蛛网膜下腔阻滞的临床研究[J].重庆医科大学学报,2005(05):105-107.
LIU Xinwei, et al. Comparison between Ropivacaine and Ropivacaine combined with Clonidine for Spinal Anaesthesia[J]. Journal of Chongqing Medical University, 2005,(5).
LIU Xinwei, et al. Comparison between Ropivacaine and Ropivacaine combined with Clonidine for Spinal Anaesthesia[J]. Journal of Chongqing Medical University, 2005,(5). DOI: 10.13406/j.cnki.cyxb.2005.05.030.
Objective:This study was to evaluate the effect of Ropivacaine for the spinal anaesthesia and the quality of analgesia and anaesthesia when clonidine was added.Methods:Spinal anaesthesia was administered to 32 ASA Ⅰ~Ⅱ degree adult patients who were randomly divided into two groups: Ropivacaine group [R=16] and Ropivacaine + Clonidine group .Data collected included;T10 spread time
maximum upper sensory level reached
and onset time and duration of zero power motor blockades
T12 regression time
pain onset time
and sedation score were also recorded.Results:The RC group onset of the T10 spread time was shorter
the maximum upper sensory level reached was higher
the onset time of zero power motor block was faster;The RC group anaesthetic regression time
the duration of zero power motor block
the time of pain onset was longer
and sedation scores was higher.Conclusion:Ropivacaine and ropivacaine combined with clonidine are sufficient to produce good sensory and motor blockade for lower abdomen and lower limb surgery under spinal anaesthesia.Addition of clonidine to Ropivacaine increase the anaesthetic potency by shortening onset time of sensation and motor block
increasing maximum upper sensory block level
prolonging regression time
and prolonging duration of the analgesic period as well as providing some sedation.