Objective:To investigate the anxiety and depression in pregnant patients with intrahepatic cholestasis.Methods:A survry was conducted among 102 pregnant patients with intrahepatic cholestasis hospitalized by using self-rating anxiety scals(SAS) and self-rating depression scale(SDS).188 normal pregnant women were established as the normal contrals.Results:The average SAS in pregnant patients with intrahepatic cholestasis hospitalized significantly higher than that in the normal pregnant women.The average SDS in pregnant patients with intrahepatic cholestasis was significantly higher than that in the normal contrals.In pregnant patients with intrahepatic cholestasis hospitalized

the average SDS in elderly primipara and the women with abnormal reproductive history was significantly higher than that in the women at child-bearing age and the women with normal reproductive history.The average SDS in teacher was significantly higher than that in secretary

clerical worker and homeworker(P<0.05).Conclusion:pregnant patients with intrahepatic cholestasis have symptoms of anxiety and depression to a certain degree.The degree of anxiety and depression is related to the reproductive history

child-bearing age and job.