
浏览全部资源
扫码关注微信
天津市口腔医院牙周病科,南开大学医学院/天津市口腔功能重建重点实验室/ 南开大学口腔医学科学研究院,天津 300041
贾 彦,Email:448762668@qq.com, 研究方向:牙周疾病诊疗。
王志涛,Email:wangzhitao6@hotmail.com。
收稿:2025-12-21,
修回:2026-01-14,
录用:2026-02-13,
纸质出版:2026-06-28
移动端阅览
贾彦,尹盼盼,张源,等.《牙周牙髓联合病变诊疗的专家共识》解读[J].重庆医科大学学报,2026,51(6):751-762.
Jia Yan,Yin Panpan,Zhang Yuan,et al.Interpretation of expert consensus on the diagnosis and therapy of endo-periodontal lesions[J].Journal of Chongqing Medical University,2026,51(6):751-762.
贾彦,尹盼盼,张源,等.《牙周牙髓联合病变诊疗的专家共识》解读[J].重庆医科大学学报,2026,51(6):751-762. DOI: 10.13406/j.cnki.cyxb.004053.
Jia Yan,Yin Panpan,Zhang Yuan,et al.Interpretation of expert consensus on the diagnosis and therapy of endo-periodontal lesions[J].Journal of Chongqing Medical University,2026,51(6):751-762. DOI: 10.13406/j.cnki.cyxb.004053.
2024年,
International Journal of Oral Science
发表了《牙周牙髓联合病变诊疗的专家共识》,该共识由南京大学医学院附属口腔医院闫福华教授和四川大学华西口腔医院周学东教授牵头制定,共识系统梳理了牙周牙髓联合病变的最新研究进展,从病因学、发病机制、分类、临床特征、诊断方法、治疗方案及预后分析等方面进行了系统总结并提出了共识建议,为临床医师提供了基于生物学和临床证据的治疗决策指导。
In 2024,
International Journal of Oral Science
published Expert consensus on the diagnosis and therapy of endo-periodontal lesions,which was led by Professor Yan Fuhua from The Affiliated Stomatological Hospital of Nanjing University School of Medicine and Professor Zhou Xuedong from West China Stomatological Hospital of Sichuan University. The consensus statement systematically summarizes the etiology,pathogenesis,classification,clinical features,diagnosis,treatment regimens,and prognosis of endo-periodontal lesions and proposes consensus recommendations,in order to provide guidance for clinicians to make decisions based on both biological and clinical evidence.
Papapanou PN , Sanz M , Buduneli N , et al . Periodontitis:consensus report of workgroup 2 of the 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions [J ] . J Clin Periodontol , 2018 , 45 ( Suppl 20 ): S162 - S170 .
Rotstein I . Interaction between endodontics and periodontics [J ] . Periodontol 2000 , 2017 , 74 ( 1 ): 11 - 39 .
Chen B , Zhu YN , Lin MK , et al . Expert consensus on the diagnosis and therapy of endo-periodontal lesions [J ] . Int J Oral Sci , 2024 , 16 ( 1 ): 55 .
Li XC , Hu L , Ma LS , et al . Severe periodontitis may influence cementum and dental pulp through inflammation,oxidative stress,and apoptosis [J ] . J Periodontol , 2019 , 90 ( 11 ): 1297 - 1306 .
Abbott PV , Castro Salgado J . Strategies for the endodontic management of concurrent endodontic and periodontal diseases [J ] . Aust Dent J , 2009 , 54 ( Suppl 1 ): S70 - S85 .
Wolf TG , Willems L , Briseño-Marroquín B . An in vitro endodontic model to quantify the accessory canal filling potential of the vertical and lateral condensation techniques [J ] . Aust Endod J , 2021 , 47 ( 2 ): 245 - 251 .
Sălceanu M , Melian A , Dascălu C , et al . Endo-periodontal lesions in endodontically treated teeth with periapical pathology [J ] . Diagnostics , 2025 , 15 ( 13 ): 1663 .
Gulabivala K , Ng YL . Factors that affect the outcomes of root canal treatment and retreatment-a reframing of the principles [J ] . Int Endod J , 2023 , 56 ( Suppl 2 ): S82 - S115 .
Ricucci D , Jr Siqueira JF . Fate of the tissue in lateral canals and apical ramifications in response to pathologic conditions and treatment procedures [J ] . J Endod , 2010 , 36 ( 1 ): 1 - 15 .
Das AC , Sahoo SK , Parihar AS , et al . Evaluation of role of periodontal pathogens in endodontic periodontal diseases [J ] . J Family Med Prim Care , 2020 , 9 ( 1 ): 239 - 242 .
Chung SH , Park YS , Bae KS , et al . Saving an integrating implant involved with endodontic implant pathology using surgical treatment [J ] . Int J Periodontics Restorative Dent , 2016 , 36 ( 6 ): 893 - 898 .
Vongsavan N , Matthews B . The permeability of cat dentine in vivo and in vitro [J ] . Arch Oral Biol , 1991 , 36 ( 9 ): 641 - 646 .
Kerns DG , Glickman GN . Endodontic and periodontal interrelationships [M ] // Cohen’s Pathways of the Pulp . Amsterdam : Elsevier , 2011 : 655 - 670 .
Pinheiro TN , Cintra LTA , Azuma MM , et al . Palatogingival groove and root canal instrumentation [J ] . Int Endod J , 2020 , 53 ( 5 ): 660 - 670 .
Heboyan A , Avetisyan A , Karobari MI , et al . Tooth root resorption:A review [J ] . Sci Prog , 2022 , 105 ( 3 ): 00368504221109217 .
Yamaguchi M , Noiri Y , Itoh Y , et al . Factors that cause endodontic failures in general practices in Japan [J ] . BMC Oral Health , 2018 , 18 ( 1 ): 70 .
Estrela C , de Almeida Decurcio D , Rossi-Fedele G , et al . Root perforations:a review of diagnosis,prognosis and materials [J ] . Braz Oral Res , 2018 , 32 ( Suppl 1 ): S73 .
Jr Siqueira JF , Rôças IN . Present status and future directions:Microbiology of endodontic infections [J ] . Int Endod J , 2022 , 55 ( Suppl 3 ): S512 - S530 .
Buonavoglia A , Lanave G , Camero M , et al . Next-generation sequencing analysis of root canal microbiota associated with a severe endodontic-periodontal lesion [J ] . Diagnostics , 2021 , 11 ( 8 ): 1461 .
Sooratgar A , Tabrizizade M , Nourelahi M , et al . Management of an endodontic-periodontal lesion in a maxillary lateral incisor with palatal radicular groove:a case report [J ] . Iran Endod J , 2016 , 11 ( 2 ): 142 - 145 .
Sonawane JM , Rai AK , Sharma M , et al . Microbial biofilms:Recent advances and progress in environmental bioremediation [J ] . Sci Total Environ , 2022 , 824 : 153843 .
Gambin DJ , Vitali FC , Casanova KAS , et al . Prevalence of species of yellow,purple and green microbial complexes in endo-perio lesions:a systematic review [J ] . Braz Oral Res , 2024 , 38 : e048 .
Asgary S , Fazlyab M . Management of failed periodontal surgical intervention for a furcal lesion with a nonsurgical endodontic approach [J ] . Restor Dent Endod , 2014 , 39 ( 2 ): 115 - 119 .
Raheja J , Tewari S , Tewari S , et al . Evaluation of efficacy of chlorhexidine intracanal medicament on the periodontal healing of concomitant endodontic-periodontal lesions without communication:an interventional study [J ] . J Periodontol , 2014 , 85 ( 8 ): 1019 - 1026 .
Singh P . Endo-perio dilemma:a brief review [J ] . Dent Res J , 2011 , 8 ( 1 ): 39 - 47 .
吴海林 , 俞少杰 , 吴风华 . 牙周牙髓联合病变与牙周感染的相关性分析 [J ] . 中华实用诊断与治疗杂志 , 2013 , 27 ( 10 ): 1017 - 1019 .
Wu HL , Yu SJ , Wu FH . Correlation analysis between combined periodontal and pulp diseases and periodontal infection [J ] . J Chin Pract Diagn Ther , 2013 , 27 ( 10 ): 1017 - 1019 .
董楠 , 刘霞 , 李 强 . 牙周源性牙周牙髓联合病变病原菌分布及临床特征分析 [J ] . 中国病原生物学杂志 , 2024 , 19 ( 10 ): 1198 - 1201 .
Dong N , Liu X , Li Q . Distribution and clinical characteristics of pathogens in combined periodontal and pulp lesions caused by periodontitis [J ] . J Pathog Biol , 2024 , 19 ( 10 ): 1198 - 1201 .
Herrera D , Retamal-Valdes B , Alonso B , et al . Acute periodontal lesions(periodontal abscesses and necrotizing periodontal diseases) and endo-periodontal lesions [J ] . J Periodontol , 2018 , 89 ( Suppl 1 ): S85 - S102 .
Ruetters M , Gehrig H , Kronsteiner D , et al . Prevalence of endo-perio lesions according to the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Disease in a university hospital [J ] . Quintessence Int , 2022 , 53 ( 2 ): 134 - 142 .
Herrera D , Retamal-Valdes B , Alonso B , et al . Acute periodontal lesions(periodontal abscesses and necrotizing periodontal diseases) and endo-periodontal lesions [J ] . J Clin Periodontol , 2018 , 45 ( Suppl 20 ): S78 - S94 .
Todd R . Cone beam computed tomography updated technology for endodontic diagnosis [J ] . Dent Clin North Am , 2014 , 58 ( 3 ): 523 - 543 .
Pope O , Sathorn C , Parashos P . A comparative investigation of cone-beam computed tomography and periapical radiography in the diagnosis of a healthy periapex [J ] . J Endod , 2014 , 40 ( 3 ): 360 - 365 .
Caton JG , Armitage G , Berglundh T , et al . A new classification scheme for periodontal and peri-implant diseases and conditions-Introduction and key changes from the 1999 classification [J ] . J Periodontol , 2018 , 89 ( Suppl 1 ): S1 - S8 .
Herrera D , Retamal-Valdes B , Alonso B , et al . Acute periodontal lesions(periodontal abscesses and necrotizing periodontal diseases) and endo-periodontal lesions [J ] . J Periodontol , 2018 , 89 ( Suppl 1 ): S85 - S102 .
Tsesis I , Fuss Z . Diagnosis and treatment of accidental root perforations [J ] . Endod Top , 2006 , 13 ( 1 ): 95 - 107 .
Klepp M . Clinical periodontology and implant dentistry [J ] . Tidende , 2009 , 119 ( 3 ): 95 - 107 .
Chu EY , Deeb JG , Foster BL , et al . Multiple idiopathic cervical root resorption: a challenge for a transdisciplinary medical-dental team [J ] . Front Dent Med , 2021 , 2 : 652605 .
Lin HJ , Chang MC , Chang SH , et al . Treatment outcome of the teeth with cemental tears [J ] . J Endod , 2014 , 40 ( 9 ): 1315 - 1320 .
Fan XM , Xu XY , Yu SW , et al . Prognostic factors of grade 2-3 endo-periodontal lesions treated nonsurgically in patients with periodontitis:a retrospective case-control study [J ] . Biomed Res Int , 2020 , 2020 : 1592910 .
Guo JH , Li Y , Lin XD , et al . Prognostic factors of combined periodontal and endodontic lesions:a retrospective study [J ] . Contrast Media Mol Imaging , 2022 , 2022 : 5042097 .
周 伟 , 汤 雅 , 李厚轩 , 等 . 牙周牙髓联合病变患牙预后观察的回顾性研究 [J ] . 口腔医学研究 , 2021 , 37 ( 9 ): 825 - 829 .
Zhou W , Tang Y , Li HX , et al . Prognostic effect of combined periodontal-endodontic lesions:a retrospective study [J ] . J Oral Sci Res , 2021 , 37 ( 9 ): 825 - 829 .
Petit C , Schmeltz S , Burgy A , et al . Risk factors associated with long-term outcomes after active and supporting periodontal treatments:impact of various compliance definitions on tooth loss [J ] . Clin Oral Investig , 2019 , 23 ( 11 ): 4123 - 4131 .
Khalighinejad N , Aminoshariae A , Kulild JC , et al . The influence of periodontal status on endodontically treated teeth:9-year survival analysis [J ] . J Endod , 2017 , 43 ( 11 ): 1781 - 1785 .
Fan JY , Caton JG . Occlusal trauma and excessive occlusal forces:narrative review,case definitions,and diagnostic considerations [J ] . J Clin Periodontol , 2018 , 45 ( Suppl 20 ): S199 - S206 .
Passanezi E , Sant’Ana ACP . Role of occlusion in periodontal disease [J ] . Periodontol 2000 , 2019 , 79 ( 1 ): 129 - 150 .
Cortellini P , Stalpers G , Mollo A , et al . Periodontal regeneration versus extraction and prosthetic replacement of teeth severely compromised by attachment loss to the apex:5-year results of an ongoing randomized clinical trial [J ] . J Clin Periodontol , 2011 , 38 ( 10 ): 915 - 924 .
Shchipkova AY , Nagaraja HN , Kumar PS . Subgingival microbial profiles of smokers with periodontitis [J ] . J Dent Res , 2010 , 89 ( 11 ): 1247 - 1253 .
Delima SL , McBride RK , Preshaw PM , et al . Response of subgingival bacteria to smoking cessation [J ] . J Clin Microbiol , 2010 , 48 ( 7 ): 2344 - 2349 .
Li YW , Jin XG , Mao LM . Protective effect of catalpol on nicotine-induced injury of alveolar bone and associated underlying mechanisms [J ] . Mol Med Rep , 2017 , 16 ( 6 ): 8345 - 8350 .
Pirani C , Iacono F , Gatto MR , et al . Outcome of secondary root canal treatment filled with Thermafil:a 5-year follow-up of retrospective cohort study [J ] . Clin Oral Investig , 2018 , 22 ( 3 ): 1363 - 1373 .
Fouad AF , Burleson J . The effect of diabetes mellitus on endodontic treatment outcome:data from an electronic patient record [J ] . J Am Dent Assoc , 2003 , 134 ( 1 ): 43 - 51 .
Dhoum S , Laslami K , Rouggani F , et al . Endo-perio lesion and uncontrolled diabetes [J ] . Case Rep Dent , 2018 , 2018 : 7478236 .
Segura-Egea JJ , Cabanillas-Balsera D , Martín-González J , et al . Impact of systemic health on treatment outcomes in endodontics [J ] . Int Endod J , 2023 , 56 ( Suppl 2 ): S219 - S235 .
Song MJ , Kim HC , Lee W , et al . Analysis of the cause of failure in nonsurgical endodontic treatment by microscopic inspection during endodontic microsurgery [J ] . J Endod , 2011 , 37 ( 11 ): 1516 - 1519 .
Sayed ME , Jurado CA , Tsujimoto A . Factors affecting clinical decision-making and treatment planning strategies for tooth retention or extraction:an exploratory review [J ] . Niger J Clin Pract , 2020 , 23 ( 12 ): 1629 - 1638 .
Takahashi K , Yamazaki K , Yamazaki M , et al . Personalized medicine based on the pathogenesis and risk assessment of endodontic-periodontal lesions [J ] . J Pers Med , 2022 , 12 ( 10 ): 1688 .
Ruiz XF , Duran-Sindreu F , Shemesh H , et al . Development of periapical lesions in endodontically treated teeth with and without periodontal involvement:a retrospective cohort study [J ] . J Endod , 2017 , 43 ( 8 ): 1246 - 1249 .
Zehnder M , Gold SI , Hasselgren G . Pathologic interactions in pulpal and periodontal tissues [J ] . J Clin Periodontol , 2002 , 29 ( 8 ): 663 - 671 .
周 伟 , 陈 斌 , 赵俊杰 , 等 . 牙周牙髓联合病变牙周治疗时机选择研究 [J ] . 口腔医学研究 , 2016 , 32 ( 6 ): 601 - 604 .
Zhou W , Chen B , Zhao JJ , et al . Research on the periodontal treatment timing for combined periodontal-endodontic lesions [J ] . J Oral Sci Res , 2016 , 32 ( 6 ): 601 - 604 .
Jin Y , Chen B , Ni YH , et al . Time lapse between endodontic and periodontal treatments of combined periodontal-endodontic lesion:a systematic review [J ] . West China J Stomatol , 2018 , 36 ( 2 ): 167 - 173 .
Sasser L . Endodontic disinfection for orthograde root canal treatment in veterinary dentistry [J ] . J Vet Dent , 2020 , 37 ( 1 ): 35 - 40 .
Fang F , Gao B , He TR , et al . Efficacy of root canal therapy combined with basic periodontal therapy and its impact on inflammatory responses in patients with combined periodontal-endodontic lesions [J ] . Am J Transl Res , 2021 , 13 ( 12 ): 14149 - 14156 .
Chubb DWR . A review of the prognostic value of irrigation on root canal treatment success [J ] . Aust Endod J , 2019 , 45 ( 1 ): 5 - 11 .
Sharma S , Deepak P , Vivek S , et al . Palatogingival groove:recognizing and managing the hidden tract in a maxillary incisor:a case report [J ] . J Int Oral Health , 2015 , 7 ( 6 ): 110 - 114 .
米热阿依克孜·马木提 , 江阿力·帕孜力别克 , 赵莉 , 等 . 根管治疗对牙周源性牙周牙髓联合病变细菌谱的影响 [J ] . 口腔医学研究 , 2021 , 37 ( 9 ): 830 - 834
Mamut MRAYKZ , Pazilbek JAL , Zhao L , et al . Effect of root canal therapy on bacterial colonization of periodontal-derived combined periodontal and endodontic lesions [J ] . J Oral Sci Res , 2021 , 37 ( 9 ): 830 - 834 .
Kurihara H , Kobayashi Y , Francisco IA , et al . A microbiological and immunological study of endodontic-periodontic lesions [J ] . J Endod , 1995 , 21 ( 12 ): 617 - 621 .
Verrusio C , Iorio-Siciliano V , Blasi A , et al . The effect of orthodontic treatment on periodontal tissue inflammation:a systematic review [J ] . Quintessence Int , 2018 , 49 ( 1 ): 69 - 77 .
Simon JH , Glick DH , Frank AL . The relationship of endodontic-periodontic lesions [J ] . J Periodontol , 1972 , 43 ( 4 ): 202 - 208 .
Mauri-Obradors E , Merlos A , Estrugo-Devesa A , et al . Benefits of non-surgical periodontal treatment in patients with type 2 diabetes mellitus and chronic periodontitis:a randomized controlled trial [J ] . J Clin Periodontol , 2018 , 45 ( 3 ): 345 - 353 .
陈 斌 , 徐蓉蓉 , 张家鼎 , 等 . 重度牙周炎患牙的保存治疗 [J ] . 国际口腔医学杂志 , 2020 , 47 ( 2 ): 125 - 130 .
Chen B , Xu RR , Zhang JD , et al . The retention of severe periodontitis-involved tooth [J ] . Int J Stomatol , 2020 , 47 ( 2 ): 125 - 130 .
Cho YD , Lee JE , Chung Y , et al . Collaborative management of combined periodontal-endodontic lesions with a palatogingival groove:a case series [J ] . J Endod , 2017 , 43 ( 2 ): 332 - 337 .
Castelo-Baz P , Ramos-Barbosa I , Martín-Biedma B , et al . Combined endodontic-periodontal treatment of a palatogingival groove [J ] . J Endod , 2015 , 41 ( 11 ): 1918 - 1922 .
李 晓 . 根尖显微外科手术治疗慢性根尖周炎研究进展 [J ] . 中国实用口腔科杂志 , 2015 , 8 ( 8 ): 508 - 512 .
Li X . Research progress of endodontics microsurgery for chronic apical periodontitis [J ] . Chin J Pract Stomatol , 2015 , 8 ( 8 ): 508 - 512 .
王密 , 尹仕海 . 根尖外科治疗的临床进展 [J ] . 牙体牙髓牙周病学杂志 , 2009 , 19 ( 11 ): 666 - 670 .
Wang M , Yin SH . Clinical progress in periapical surgery [J ] . Chin J Conserv Dent , 2009 , 19 ( 11 ): 666 - 670 .
Dong X , Su Q , Li W , et al . The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery:a randomized controlled trial [J ] . Clin Oral Investig , 2024 , 28 ( 3 ): 188 .
Oh SL , Fouad AF , Park SH . Treatment strategy for guided tissue regeneration in combined endodontic-periodontal lesions:case report and review [J ] . J Endod , 2009 , 35 ( 10 ): 1331 - 1336 .
Abbott PV , Salgado JC . Strategies for the endodontic management of concurrent endodontic and periodontal diseases [J ] . Aust Dent J , 2009 , 54 ( Suppl 1 ): S70 - S85 .
Britain SK , von Arx T , Schenk RK , et al . The use of guided tissue regeneration principles in endodontic surgery for induced chronic periodontic-endodontic lesions:a clinical,radiographic,and histologic evaluation [J ] . J Periodontol , 2005 , 76 ( 3 ): 450 - 460 .
Schallhorn RA , McClain PK . Periodontal regeneration:management of periodontal osseous defects by the periodontist-dental hygienist team [J ] . J Evid Based Dent Pract , 2014 ,14 Suppl : S42 - S52 .
刘琼 , 孙 江 . 引导组织再生术治疗牙周牙髓联合病变的观察 [J ] . 广东牙病防治 , 2011 , 19 ( 4 ): 202 - 205
Liu Q , Sun J . Bone graft and guided tissue regeneration in treatment for combined periodontic-endodontic lesion [J ] . J Prev Treat Stomatol Diaeases , 2011 , 19 ( 4 ): 202 - 205 .
李万红 , 林 军 , 朱婉萍 . 半导体激光模拟根管内照射抗菌效应的实验研究 [J ] . 现代口腔医学杂志 , 2006 , 20 ( 6 ): 632 - 633 .
Li WH , Lin J , Zhu WP . An experimental study on bactericidal effects of diode laser simulated irradiation in root canal [J ] . J Mod Stomatol , 2006 , 20 ( 6 ): 632 - 633 .
Neelakantan P , Cheng CQ , Mohanraj R , et al . Antibiofilm activity of three irrigation protocols ac tivated by ultrasonic,diode laser or Er:YAG laser in vitro [J ] . Int Endod J , 2015 , 48 ( 6 ): 602 - 610 .
Gutknecht N , van Gogswaardt D , Conrads G , et al . Diode laser radiation and its bactericidal effect in root canal wall dentin [J ] . J Clin Laser Med Surg , 2000 , 18 ( 2 ): 57 - 60 .
黎远皋 , 王 霄 , 徐菁玲 , 等 . 半导体激光辅助治疗牙周牙髓联合病变的临床研究 [J ] . 华西口腔医学杂志 , 2012 , 30 ( 2 ): 161 - 164,168 .
Li YG , Wang X , Xu JL , et al . The clinical study on the use of diode laser irradiation in the treatment of periodontal-endodontic combined lesions [J ] . West China J Stomatol , 2012 , 30 ( 2 ): 161 - 164,168 .
冯 丹 , 聂敏海 . 激光联合药物修复牙周-牙髓联合病变的对比研究 [J ] . 中国现代医学杂志 , 2019 , 29 ( 1 ): 93 - 98 .
Feng D , Nie MH . Comparative study of laser and drug in treatment of combined periodontal-endodontic lesions [J ] . China J Mod Med , 2019 , 29 ( 1 ): 93 - 98 .
Gursoy H , Ozcakir-Tomruk C , Tanalp J , et al . Photodynamic therapy in dentistry:a literature review [J ] . Clin Oral Investig , 2013 , 17 ( 4 ): 1113 - 1125 .
Andrade PF , Garlet GP , Silva JS , et al . Adjunct effect of the antimicrobial photodynamic therapy to an association of non-surgical and surgical periodontal treatment in modulation of gene expression:a human study [J ] . J Photochem Photobiol B , 2013 , 126 : 119 - 125 .
栾秀玲 , 胡艳秋 , 秦艳利 . 甲苯胺蓝为光敏剂的光动力疗法对龈下菌斑灭菌效果的研究 [J ] . 口腔医学研究 , 2012 , 28 ( 3 ): 233 - 236 .
Luan XL , Hu YQ , Qin YL . The effect of inactivation periodontal pathogens of subgingival plaques in vitro with toluidine blue(TB)-mediated photodynamic therapy [J ] . J Oral Sci Res , 2012 , 28 ( 3 ): 233 - 236 .
Prates RA , Yamada AM , Suzuki LC , et al . Histomorphometric and microbiological assessment of photodynamic therapy as an adjuvant treatment for periodontitis:a short-term evaluation of inflammatory periodontal conditions and bacterial reduction in a rat model [J ] . Photomed Laser Surg , 2011 , 29 ( 12 ): 835 - 844 .
Cortellini P , Stalpers G , Mollo A , et al . Periodontal regeneration versus extraction and dental implant or prosthetic replacement of teeth severely compromised by attachment loss to the apex:A randomized controlled clinical trial reporting 10-year outcomes,survival analysis and mean cumulative cost of recurrence [J ] . J Clin Periodontol , 2020 , 47 ( 6 ): 768 - 776 .
Tietmann C , Tezer I , Youssef E , et al . Management of teeth with grade 3 endo-periodontal lesions by combined endodontic and regenerative periodontal therapy [J ] . J Clin Med , 2023 , 13 ( 1 ): 93 .
Romeo E , Storelli S . Systematic review of the survival rate and the biological,technical,and aesthetic complications of fixed dental prostheses with cantilevers on implants reported in longitudinal studies with a mean of 5 years follow-up [J ] . Clin Oral Implants Res , 2012 , 23 ( Suppl 6 ): S39 - S49 .
0
浏览量
3
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621