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Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study
Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study
- Burns & Trauma 2022年10卷第1期
- 作者机构：
1. Polymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry, Department of Organic and Macromolecular Chemistry, Ghent University
2. Smart Polymeric Biomaterials Research Group, Biomaterials and Tissue Engineering (SIEM) @ Campus Group T Leuven
- 作者简介：
- 基金信息：MM would like to thank Fonds Wetenschappelijk Onderzoek (FWO) for financial support (SB PhD fellow at FWO, Grant No. 3SB5619). AM has also received funding from Fonds Wetenschappelijk Onderzoek (Grant No. 12Z2918N).
DOI：10.1093/burnst/tkac024
中图分类号：纸质出版日期：2022，
网络出版日期：2022-6-21，
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Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study[J]. Burns & Trauma, 2022,10(1).
Manon Minsart, Sandra Van Vlierberghe, Peter Dubruel, Arn Mignon, Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study, Burns & Trauma, Volume 10, 2022, tkac024, https://doi.org/10.1093/burnst/tkac024
Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study[J]. Burns & Trauma, 2022,10(1). DOI： 10.1093/burnst/tkac024.
Manon Minsart, Sandra Van Vlierberghe, Peter Dubruel, Arn Mignon, Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study, Burns & Trauma, Volume 10, 2022, tkac024, https://doi.org/10.1093/burnst/tkac024 DOI：
摘要
Abstract
BackgroundNowadays
a wide range of wound dressings is already commercially available. The selection of the dressing is of paramount importance as inappropriate wound management and dressing selection can delay the wound healing process. Not only can this be distressing for the patient
but it can also contribute to complications such as maceration and subsequent infection. Many researchers are targeting the design of dressings with superior properties over existing commercial dressings. However
reported results in the state-of-the-art are rarely benchmarked against commercial dressings. The aim of this study was to determine several characteristics of a large variety of the most frequently used commercial wound dressings
providing an overview for both practitioners and researchers.MethodsFor this comparative study
11 frequently used commercial wound dressings were selected
representing the different types. The morphology was studied using scanning electron microscopy. The dressings were characterized in terms of swelling capacity (water
phosphate buffered saline and simulated wound fluid)
moisture vapour transmission rate (MVTR) and moisture uptake capacity (via dynamic vapour sorption) as well as mechanical properties using tensile testing and texturometry.ResultsThe selected dressings showed distinctive morphological differences (fibrous
porous and/or gel) which was reflected in the different properties. Indeed
the swelling capacities ranged between 1.5 and 23.2 g/g (water)
2.1 and 17.6 g/g (phosphate buffered saline) or 2.9 and 20.8 g/g (simulated wound fluid). The swelling capacity of the dressings in water increased even further upon freeze-drying
due to the formation of pores. The MVTR values varied between 40 and 930 g/m2/24 h. The maximal moisture uptake capacity varied between 5.8% and 105.7% at 95% relative humidity. Some commercial dressings exhibited a superior mechanical strength
due to either being hydrophobic or multi-layered.ConclusionsThe present work not only offers insight into a valuable toolbox of suitable wound dressing characterization techniques
but also provides an extensive landscaping of commercial dressings along with their physico-chemical properties
obtained through reproducible experimental protocols. Furthermore
it ensures appropriate benchmark values for commercial dressings in all forthcoming studies and could aid researchers with the development of novel modern wound dressings. The tested dressings either exhibited a high strength or a high swelling capacity
suggesting that there is still a strong potential in the wound dressings market for dressings that possess both.
关键词
Keywords
Wound dressingsBurnsExuding woundsWound healingExudate managementPhysico-chemical
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