3D printing of functional nerve guide conduits

Yulan Huang; Wenbi Wu; Haofan Liu; Yuwen Chen; Bo Li; Zhiyuan Gou; Xun Li; Maling Gou

doi:10.1093/burnst/tkab011

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3D printing of functional nerve guide conduits

更新时间：2022-06-14

- 3D printing of functional nerve guide conduits
- 3D printing of functional nerve guide conduits
- Burns & Trauma 2021年9卷第1期
- 作者机构：
  
  1. State Key Laboratory of Biotherapy and Cancer Center
  2. Sichuan University
  3. Department of Ophthalmology
- 作者简介：
- 基金信息：
- DOI：10.1093/burnst/tkab011
  中图分类号：
- 纸质出版日期：2021，
  
  网络出版日期：2021-5-7，
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Yulan Huang, Wenbi Wu, Haofan Liu, 等. 3D printing of functional nerve guide conduits[J]. Burns & Trauma, 2021,9(1).

Yulan Huang, Wenbi Wu, Haofan Liu, Yuwen Chen, Bo Li, Zhiyuan Gou, Xun Li, Maling Gou, 3D printing of functional nerve guide conduits, Burns & Trauma, Volume 9, 2021, tkab011, https://doi.org/10.1093/burnst/tkab011
Yulan Huang, Wenbi Wu, Haofan Liu, 等. 3D printing of functional nerve guide conduits[J]. Burns & Trauma, 2021,9(1). DOI： 10.1093/burnst/tkab011.

Yulan Huang, Wenbi Wu, Haofan Liu, Yuwen Chen, Bo Li, Zhiyuan Gou, Xun Li, Maling Gou, 3D printing of functional nerve guide conduits, Burns & Trauma, Volume 9, 2021, tkab011, https://doi.org/10.1093/burnst/tkab011 DOI：

摘要

Abstract

Nerve guide conduits (NGCs)

as alternatives to nerve autografts and allografts

have been widely explored as an advanced tool for the treatment of peripheral nerve injury. However

the repairing efficiency of NGCs still needs significant improvements. Functional NGCs that provide a more favorable microenvironment for promoting axonal elongation and myelination are of great importance. In recent years

3D printing technologies have been widely applied in the fabrication of customized and complex constructs

exhibiting great potential for tissue engineering applications

especially for the construction of functional NGCs. In this review

we introduce the 3D printing technologies for manufacturing functional NGCs

including inkjet printing

extrusion printing

stereolithography-based printing and indirect printing. Further

we summarize the current methods and strategies for constructing functional NGCs

such as designing special conduit architectures

using appropriate materials and co-printing with different biological cues. Finally

the challenges and prospects for construction of functional NGCs are also presented.

关键词

Keywords

Nerve guide conduitsFunctionalizationPeripheral nerve repair3D printing

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