Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases

Chen Dong; Minhui Zhu; Luguang Huang; Wei Liu; Hengxin Liu; Kun Jiang; Zhou Yu; Xianjie Ma

doi:10.1093/burnst/tkaa037

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Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases

更新时间：2022-06-14

- Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases
- Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases
- Burns & Trauma 2021年9卷第1期
- 作者机构：
  
  1. Department of Plastic Surgery
  2. Fourth Military Medical University
  3. Department of Burn and Plastic Surgery
  4. Information Center
- 作者简介：
- 基金信息：
  
  The authors have no related financial interests or commercial associations. Funding from the National Natural Science Foundation of China (81671925, 81971851), the Shaanxi Province Key R&D Program Project (2018ZDXM-SF-081) and the Discipline Promotion Project of Xijing Hospital (XJZT19D03) were received for this study.
- DOI：10.1093/burnst/tkaa037
  中图分类号：
- 纸质出版日期：2021，
  
  网络出版日期：2021-1-4，
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Chen Dong, Minhui Zhu, Luguang Huang, 等. Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases[J]. Burns & Trauma, 2021,9(1).

Chen Dong, Minhui Zhu, Luguang Huang, Wei Liu, Hengxin Liu, Kun Jiang, Zhou Yu, Xianjie Ma, Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases, Burns & Trauma, Volume 9, 2021, tkaa037, https://doi.org/10.1093/burnst/tkaa037
Chen Dong, Minhui Zhu, Luguang Huang, 等. Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases[J]. Burns & Trauma, 2021,9(1). DOI： 10.1093/burnst/tkaa037.

Chen Dong, Minhui Zhu, Luguang Huang, Wei Liu, Hengxin Liu, Kun Jiang, Zhou Yu, Xianjie Ma, Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases, Burns & Trauma, Volume 9, 2021, tkaa037, https://doi.org/10.1093/burnst/tkaa037 DOI：

摘要

Abstract

BackgroundTissue expansion is used for scar reconstruction owing to its excellent clinical outcomes; however

the complications that emerge from tissue expansion hinder repair. Infection is considered a major complication of tissue expansion. This study aimed to analyze the perioperative risk factors for expander infection.MethodsA large

retrospective

single-institution observational study was carried out over a 10-year period. The study enrolled consecutive patients who had undergone tissue expansion for scar reconstruction. Demographics

etiological data

expander-related characteristics and postoperative infection were assessed. Univariate and multivariate logistic regression analysis were performed to identify risk factors for expander infection. In addition

we conducted a sensitivity analysis for treatment failure caused by infection as an outcome.ResultsA total of 2374 expanders and 148 cases of expander infection were assessed. Treatment failure caused by infection occurred in 14 expanders. Multivariate logistic regression analysis identified that disease duration of ≤1 year (odds ratio (OR)

2.07; p < 0.001)

larger volume of expander (200–400 ml vs <200 ml; OR

1.74; p = 0.032; >400 ml vs <200 ml; OR

1.76; p = 0.049)

limb location (OR

2.22; p = 0.023) and hematoma evacuation (OR

2.17; p = 0.049) were associated with a high likelihood of expander infection. Disease duration of ≤1 year (OR

3.88; p = 0.015) and hematoma evacuation (OR

10.35; p = 0.001) were so related to high risk of treatment failure.ConclusionsThe rate of expander infection in patients undergoing scar reconstruction was 6.2%. Disease duration of <1 year

expander volume of >200 ml

limb location and postoperative hematoma evacuation were independent risk factors for expander infection.

关键词

Keywords

Tissue expansionTissue expanderScar reconstructionRisk factorsInfection

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