Assessing keloid recurrence following surgical excision and radiation

Michael H Gold; Mark S Nestor; Brian Berman; David Goldberg

doi:10.1093/burnst/tkaa031

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Assessing keloid recurrence following surgical excision and radiation

更新时间：2022-06-09

- Assessing keloid recurrence following surgical excision and radiation
- Assessing keloid recurrence following surgical excision and radiation
- Burns & Trauma 2020年8卷第1期
- 作者机构：
  
  1. Gold Skin Care Center
  2. Center for Clinical and Cosmetic Research
  3. Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine
  4. Skin Laser & Surgery Specialists of NY/NJ
- 作者简介：
- 基金信息：
  
  Funding for manuscript assistance was provided by Sensus Healthcare, Boca Raton, FL. Sensus Healthcare manufactures a device cleared for the treatment of keloids.
- DOI：10.1093/burnst/tkaa031
  中图分类号：
- 纸质出版日期：2020，
  
  网络出版日期：2020-11-14，
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Michael H Gold, Mark S Nestor, Brian Berman, 等. Assessing keloid recurrence following surgical excision and radiation[J]. Burns & Trauma, 2020,8(1).

Michael H Gold, Mark S Nestor, Brian Berman, David Goldberg, Assessing keloid recurrence following surgical excision and radiation, Burns & Trauma, Volume 8, 2020, tkaa031, https://doi.org/10.1093/burnst/tkaa031
Michael H Gold, Mark S Nestor, Brian Berman, 等. Assessing keloid recurrence following surgical excision and radiation[J]. Burns & Trauma, 2020,8(1). DOI： 10.1093/burnst/tkaa031.

Michael H Gold, Mark S Nestor, Brian Berman, David Goldberg, Assessing keloid recurrence following surgical excision and radiation, Burns & Trauma, Volume 8, 2020, tkaa031, https://doi.org/10.1093/burnst/tkaa031 DOI：

摘要

Abstract

Keloids are a fibroproliferative disorder that can result from a cutaneous injury to the reticular dermis. Recurrence rates as high as 100% have been reported following surgical excision alone. Consequently

a variety of post-surgical techniques have been employed to prevent keloid recurrence

including the use of radiation. Although numerous studies have shown post-excisional X-rays

electron beam

lasers and brachytherapy can reduce the rate of keloid recurrence

numerous inconsistencies

including a wide range of definitions for keloid recurrence

make it difficult to compare study outcomes. The review aims to examine the various means for defining keloid recurrence in clinical trials involving the use of radiation therapy.Searches of the Cochrane Library and PubMed were performed to identify the available information for post-surgical keloid recurrence following radiation therapy. Each identified study was reviewed for patient follow-up and criteria used to define keloid recurrence. The search results included clinical studies with external beam radiation

brachytherapy and superficial radiation therapy. Many studies did not include a definition of keloid recurrence

or defined recurrence only as the return of scar tissue. Other studies defined keloid recurrence based on patient self-assessment questionnaires

symptoms and scar elevation and changes in Kyoto Scar Scale

Japan Scar Workshop Scale and Vancouver Scar Scale scores.The results of this review indicate keloidectomy followed by radiation therapy provide satisfactory recurrence rates; however

clinical studies evaluating these treatments do not describe treatment outcomes or use different definitions of keloid recurrence. Consequently

recurrence rates vary widely

making comparisons across studies difficult. Keloid recurrence should be clearly defined using both objective and subjective measures.

关键词

Keywords

KeloidKeloid scarRecurrenceExternal beam radiationBrachytherapySuperficial radiation therapy

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