1. Hubei Hongshan Laboratory, College of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University,Hubei,Wuhan,PR China,430070

2. Hubei Clinical Research Center for Precise Diagnosis and Treatment of Liver Cancer, Taihe Hospital, Hubei University of Medicine,Hubei,Shiyan,PR China,442000

3. Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center,TX,Houston,USA,77030

4. The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences,TX,Houston,USA,77030