miR-106b as an emerging therapeutic target in cancer

Surendra Kumar Sagar

doi:10.1016/j.gendis.2021.02.002

您当前的位置：

首页 >

文章列表页 >

miR-106b as an emerging therapeutic target in cancer

Review article | 更新时间：2022-06-24

- miR-106b as an emerging therapeutic target in cancer
- miR-106b as an emerging therapeutic target in cancer
- Genes & Diseases 2022年9卷第4期
- 作者机构：
  
  Department of Zoology, Swami Shraddhanand College, University of Delhi, Delhi,India,110036
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2021.02.002
  中图分类号：
- 纸质出版日期：2022，
  
  网络出版日期：2022-7-1，
扫描看全文
Surendra Kumar Sagar. miR-106b as an emerging therapeutic target in cancer[J]. Genes & Diseases, 2022,9(4).

Surendra Kumar Sagar. miR-106b as an emerging therapeutic target in cancer[J]. Genes & Diseases, 2022,9(4).
Surendra Kumar Sagar. miR-106b as an emerging therapeutic target in cancer[J]. Genes & Diseases, 2022,9(4). DOI： 10.1016/j.gendis.2021.02.002.

Surendra Kumar Sagar. miR-106b as an emerging therapeutic target in cancer[J]. Genes & Diseases, 2022,9(4). DOI： 10.1016/j.gendis.2021.02.002.

摘要

Abstract

MicroRNAs (miRNAs) comprise short non-coding RNAs that function in regulating the expression of tumor suppressors or oncogenes and modulate oncogenic signaling pathways in cancer. miRNAs expression alters significantly in several tumor tissues and cancer cell lines. For example

miR-106b functions as an oncogene and increases in multiple cancers. The miR-106b directly targets genes involved in tumorigenesis

proliferation

invasion

migration

and metastases. This review has focused on the miR-106b function and its downstream target in different cancers and provide perspective into how miR-106 regulates cancer cell proliferation

migration

invasion

and metastases by regulating the tumor suppressor genes. Since miRNAs-based therapies are currently being developed to enhance cancer therapy outcomes

miR-106b could be an attractive and prospective candidate in different cancer types for detection

diagnosis

and prognosis assessment in the tumor.

关键词

Keywords

ApoptosisCancerMetastasesmiRNAOncogeneTumor suppressor

references

查看原文

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

MicroRNA-9 as a paradoxical but critical regulator of cancer metastasis: Implications in personalized medicine

Autophagy-related lncRNAs in tumor progression and drug resistance: A double-edged sword

DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer

A novel aptamer-based small RNA delivery platform and its application to cancer therapy

Chaperone-assisted E3 ligase CHIP: A double agent in cancer