The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine

Yin Li; Yihan Zhang; Yuhao Zou; Shiwei Duan

doi:10.1016/j.gendis.2020.09.007

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The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine

Review article | 更新时间：2022-06-24

- The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
- The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
- Genes & Diseases 2022年9卷第3期
- 作者机构：
  
  Medical Genetics Center, Ningbo University School of Medicine,Zhejiang,Ningbo,PR China,315211
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2020.09.007
  中图分类号：
- 纸质出版日期：2022，
  
  网络出版日期：2022-5-1，
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Yin Li, Yihan Zhang, Yuhao Zou, 等. The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine[J]. Genes & Diseases, 2022,9(3).

Yin Li, Yihan Zhang, Yuhao Zou, et al. The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine[J]. Genes & Diseases, 2022,9(3).
Yin Li, Yihan Zhang, Yuhao Zou, 等. The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine[J]. Genes & Diseases, 2022,9(3). DOI： 10.1016/j.gendis.2020.09.007.

Yin Li, Yihan Zhang, Yuhao Zou, et al. The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine[J]. Genes & Diseases, 2022,9(3). DOI： 10.1016/j.gendis.2020.09.007.

摘要

Abstract

MiR-4295

located on chromosome 10q25.2

is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed

in vivo

participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers

it has also been found to have the function of inhibiting cancer. At the same time

the expression of miR-4295 is related to prognosis and can be affected by numerous factors connecting to the therapeutic effects of various drugs. This article is to better summarize the role of miR-4295 in cancer and review the potential diagnostic

prognostic

and therapeutic value of miR-4295

which may provide insight into subsequent research.

关键词

Keywords

CancerCancer cellsmiR-4295Molecular functionPrognosisTumor suppressor

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