MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma

FengXia Gao; SiRong He; AiShun Jin

doi:10.1016/j.gendis.2020.08.006

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MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma

Review article | 更新时间：2022-06-24

- MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma
- MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma
- Genes & Diseases 2021年8卷第5期
- 作者机构：
  
  1. Department of Immunology, Chongqing Medical University,Chongqing,PR China,400010
  2. Chongqing Key Laboratory of Tumor Immunology and Tumor Immunotherapy, Chongqing Medical University, No.1, Medical School Road, Yuzhong District,Chongqing,PR China,400010
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2020.08.006
  中图分类号：
- 纸质出版日期：2021，
  
  网络出版日期：2021-9-1，
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FengXia Gao, SiRong He, AiShun Jin. MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma[J]. Genes & Diseases, 2021,8(5).

FengXia Gao, SiRong He, AiShun Jin. MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma[J]. Genes & Diseases, 2021,8(5).
FengXia Gao, SiRong He, AiShun Jin. MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma[J]. Genes & Diseases, 2021,8(5). DOI： 10.1016/j.gendis.2020.08.006.

FengXia Gao, SiRong He, AiShun Jin. MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma[J]. Genes & Diseases, 2021,8(5). DOI： 10.1016/j.gendis.2020.08.006.

摘要

Abstract

The important role of lncRNAs and miRNAs in directing immune responses has become increasingly clear. Recent evidence conforms that miRNAs and lncRNAs are involved in NK cell biology and diseases through RNA–protein

RNA–RNA

or RNA–DNA interactions. In this view

we summarize the contribution of miRNAs and lncRNAs to NK cell lineage development

activation and function

highlight the biological significance of functional miRNAs or lncRNAs in NKTL and discuss the potential of these miRNAs and lncRNAs as innovative biomarkers/targets for NKTL early diagnosis

target treatment and prognostic evaluations.

关键词

Keywords

ActivationDevelopmentFunctionlncRNAsmiRNANK cell BiologyNK/T-cell lymphoma

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