Objective　This paper discusses the instructional design of General survey of medi-cal culture， to provide the basis for the implementation of the teaching. Methods　The first round of our teaching situation was concluded， to improve the teaching objectives， content， methods and the content and methods of teaching evaluation. Results　The course is a new medical humanities curriculum to improve medical knowledge of the human spirit of nursing students， training the cultural literacy， but the teaching content should be combined with professional features， and teaching evaluation methods should be improved. Conclusions　Rigorous designed curriculum， flexible and diverse teaching methods and forms of assessment and suggestions from the students are conducive to the improvement of the course.