Neurology is one of the most difficult subjects in clinical medical education. How to improve the teaching model of neurology is a crucial problem. The systematic instructional design and problem-based learning (PBL) emerge as mature teaching techniques

and having a broad application prospect. However

simple PBL teaching model has not achieved the desired results

because PBL teaching method pays excessive attention to the subjective initiative of students

but ignores the super-vision and assessment mechanisms

such as assessment

feedback

adjustment

which are the major concerns of systematic instructional design. This research tries to combine systematic instructional de-sign with PBL teaching model

and explore the position in neurology teaching. By determining the teaching target

analysis of PBL teaching

writing teaching plans

organization of PBL teaching

feed-back to adjust teaching design method

the final summative evaluation is done and the teaching

was completed. After practice tips may bring progress on neurology teaching mode.