Objective　To teach neurosurgical residents of standardized training by using teaching method with multi-modality visualization and to explore its application effects. Methods　Total 122 students were randomly divided into two groups: multi-modality visualization teaching group (n=61) and traditional teaching group (n=61). The evaluation of teaching effect was conducted by questionnaire of students and the analysis of test scores after the course. Comparison between the two groups was made by using independent sample t test. Results　Questionnaire showed that the satisfaction of teaching mode (88.5%)

learning efficiency (93.4%)

and training results (90.1%) with multi-modality visualization teaching group were statistically higher than traditional group (P<0.05). Test score showed that results of theory test (88.5±5.1)

on-spot examination (91.6±5.5)

and overall score (89.3±5.2) were also statistically higher in multi-modality visualization teaching group than that of control group (P<0.05). There was no significant difference in clinical skills assessment between two groups. Conclusions　Teaching with multi-modality visualization can significantly improve the efficiency of neurosurgical clinical teaching and promote the training effect of students

which provides a new strategy of neurosurgical clinical teaching.