Objective　To explore the intervention effect of the combination of medicine and education on teachers and parents of children with attention deficit hyperactivity disorder (ADHD). Methods The students in Grade 1 to 3 of 6 public primary school (6~11 years old) were enrolled by stratified sampling method and randomly divided into the experimental group and the control group. All the students were screened for ADHD

and the children diagnosed with ADHD and their parents and teachers were enrolled into study as the research object. The children in the control group were given oral short-effect methylphenidate hydrochloride tablets and their parents underwent routine health education

while the parents and teachers in the experimental group were given both the routine health education and systematic training. Before and after training

the awareness rates of ADHD knowledge among parents and teachers were observed

and the clinical effects of two groups were compared. Results　The control group included 71 children with ADHD

71 pairs of parents and 31 teachers

while the experimental group included 68 children with ADHD

68 pairs of parents and 34 teachers. The difference of general data between the two groups has no statistical significance (P>0.05). Before intervention

there was no significant difference in awareness rate of ADHD knowledge among teachers and parents in the two groups (P>0.05). After the intervention

the awareness rate of ADHD knowledge in teachers of the control group did not change obviously

while which in parents of the control group and the parents and teachers in the experimental group were significantly improved

and the improvement effect in the experimental group was significantly better than that of the control group (P<0.05). The scores of the SNAP-IV scale in both groups were significantly decreased

and the scores of the experimental group were significantly lower than those in the control group. The significant rate and total effective rates of the experimental group were significantly higher than those in the control group (P<0.05). Conclusion　The intervention effect of combination of medicine and education on teachers and parents of children with ADHD is definite

which is worthy of further research.