Objective To evaluate an innovative teaching mode of obstetrics and gynecology in students clinical probation. Methods A total of 195 students from 2015 Clinical Medicine were involved in this teaching reform. The teaching mode was based on organ integration medicine

emphasing problem based learning

teacher-student interaction

creative courses as well as clinical practice. The results were evaluated by objective structured clinical examination(OSCE)and questionnaire surveys. Results The OSCE scores of the 2018 group were higher than those of the other two groups and the difference was statistically significant (p<0.05). The results of the questionnaire showed that the 2018 groups satisfaction with all aspects of the teaching mode was higher than the historical period (p<0.05). Conclusion The present innovative teaching mode could promote students’ ability to integrate theory with practice

expand clinical thinking and cultivate the innovation ability.