Objective To explore a method of applying Micro-course in medical imaging teaching reform and to evaluate its effect. Methods　The Micro-course platform was constructed by means of network and digital information technology

and micro-courses were made and uploaded. Two large classes of five-year clinical medical students attending medical imaging courses were randomly selected as control group (n=84) and experimental group (n=86). At the end of the course

the academic and practical skills of the two groups of students were compared

and the teaching situation was investigated by scores of electronic questionnaires to evaluate the effect of the method. Results　The application of Micro-course platform was successful. The scores for theoretical and practical examination of the experimental group were higher than those of the control group

and the difference was statistically significant (P<0.05). 163 valid questionnaires were retrieved. Compared to the control group

the experimental Micro-course had a higher total score in the 7 positive items

and the difference was statistically significant (P<0.05). Conclusion　Micro-course has a positive effect on the teaching reform of medical imaging.