This paper aims to explore a new way to cultivate college students' autonomous learning ability by taking the flipped classroom teaching of molecular medicine in medical colleges as an example. In view of the specific teaching content and characteristics of molecular medicine

we formulated a mixed teaching plan based on flipped classroom. By setting the teaching objectives and tasks beforehand

students were guided to explore and acquire knowledge independently from the abundant teaching resources library. In order to test the effect of students' autonomous learning and expand the cultivation of students' ability of information collection and processing

inquiry initiation

and communication and cooperation

we launched classroom discussions

communications

questions answering and group collaborative research topic-based reports. Through the reform of teaching assessment system

students' autonomous learning status can be effectively monitored to help ensure the implementation of the flipped classroom.