Objective　To investigate the training effect of the case-based learning (CBL) teaching method on post competency of medical students. Methods　Four classes of students majoring in nursing in China Medical University were enrolled and divided into experimental group and control group

with two classes in each group. In the teaching of medical chemistry

the CBL teaching method was adopted for the experimental group and the traditional teaching method was adopted for the control group

with the same teacher and teaching materials. Questionnaire survey and final examination were performed to assess the effect of the CBL teaching method on post competency of medical students

and SPSS 20.0 software was used for data analysis. Results　The results of the questionnaire survey showed that the experimental group had better assessment indices of post competency. The results of the final examination showed that the experimental group had a significantly higher mean score of medical chemistry than the control group [（73.5±10.3） vs. （６８.1±9.1）]. Conclusion　The application of the CBL teaching method in medical chemistry can effectively improve the learning outcomes of medical students and train their post competency

and therefore

it holds promise for application in the teaching of basic medicine.