Objective　The aim of this study was to evaluate the value for CBL and LBL teaching method in the training of refresher doctors in reproductive medicine. Methods　A questionnaire survey was conducted among 186 refresher doctors who had studied in the reproductive medicine center at Peking University Third Hospital from January 2016 and December 2017 one year after their graduation. We tested 33 refresher doctors in observe group and 33 refresher doctors in the CBL+LBL group who graduated at the same period. Results　Ninety-two refresher doctors responded to the investigation. The questionnaire survey showed that 84.78% of the refresher doctors thought that CBL and LBL teaching method could improve their learning abilities

clinical problem analysis and solving skills

and surgical techniques

which was conducive to promoting their assisted reproductive technology. Besides

63.04% of refresher doctors believed this method improved their research abilities. In CBL+LBL group

examination scores of theoretical knowledge were significantly higher than the observe group (P<0.05). Conclusion　The combination of CBL and LBL is effective and feasible in the training of refresher doctors in reproductive medicine.