Objective　To explore the effects of applying case-based teaching in the clinical education of ophthalmology. Methods　The experimental control method was adopted in the study

with case-based teaching method in experimental group and traditional lecture-based learning in control group. The teaching effect was evaluated through theoretical test

case analysis score and the data of questionnaire investigation. Results　In theoretical examination

the scores and score ≥ 80 rates of the experimental group were significantly higher than that of the control group (P<0.05)

the results of differential diagnosis and total results in case analysis in the experimental group were higher than those in the control group

and there was significant difference (P<0.05). The results of the questionnaire showed that the students in the experimental group were more satisfied than those in the control group in terms of improving their learning interest and efficiency

clinical thinking ability

communication ability

teamwork spirit and satisfaction with teaching methods (P<0.05). Conclusion　Comprehensive case-based teaching have achieved good results in ophthalmology teaching

which could motivate students' interest

improve the clinical ability and overall quality and it’s favorable to improve the teaching quality in this field.