Objective　To investigate the application effect of Mini-Clinical Evaluation Exercise (Mini-CEX) in the training of patient-doctor communication ability of interns in department of neurology. Methods　A total of 60 clinical interns who received practice teaching in Department of Neurology in The Third Affiliated Hospital of Army Medical University from January 2016 to June 2017 were selected

and a questionnaire survey on the communication barriers between patients and doctors was performed on admission to analyze the main causes of these barriers. The Mini-CEX was used for communication ability training of interns

and its application effect was evaluated. Results　At the end of training (one month later)

the number of patient-doctor communication

completeness of medical history collection

physical examination kills and the median and pass rate of patient satisfaction of interns were significantly improved

as compared with before (P<0.05)

and the degree of satisfaction with Mini-CEX reached above 95% among the teachers and clinical interns. Conclusion　Mini-CEX for communication ability training can improve the patient-doctor communication ability of interns in department of neurology. Mini-CEX also has a certain teaching effect and thus holds promise for application in practice teaching.