Objective　To investigate the application and effect of clinical pathway in practice teaching of hepatic surgery. Methods　The 64 clinical interns who had an internship in our department between February 2018 and May 2019 were divided randomly into two groups: the experimental group (n=32) and the control group (n=32). The clinical pathway teaching method was used in the experimental group and the traditional teaching method was used in the control group. At the end of their internship

the examination and the satisfaction survey were requested to finish in the both groups. The statistical software SPSS 17.0 was used. Continuous variables were analyzed through the t-test. Categorical data were compared through Pearson chi-square. Results　The examination results included theoretical knowledge (P=0.033)

operating skill (P=0.021)

case analysis (P=0.006) and medical record writing (P=0.017)

which were significantly better in the experimental group than in the control group

and the satisfaction of interns was also significantly better in the experimental than in the control group (P<0.05). Conclusion　The clinical pathway teaching method is effective in practice teaching of hepatic surgery

and can improve the results of practice teaching quality obviously.