Objective　This paper aims to probe into the effect of working and studying com-bined teaching reform of clinical medicine major. Methods　Two classes containing 46 students respec-tively were selected at random as observation group and control group， from the six classes of Grade Two majoring in clinical medicine. The two groups of students were trained by adopting working and studying combined teaching model and traditional teaching model respectively

after which they were evaluated in terms of clinical theory， practical skills and operations， and exercitation achievement. Results　The observation group does better in practical skills and exercitation achievement than the control group， while they have no difference in clinical theory. Conclusion　Ｗorking and studying combined teaching model can improve students' clinical analytical ability

strengthen their awareness of medical morals， and help them achieve more in exercitation.