Aim: To develop the interacting learning mode in simulative situation on “sex and health” courses for college students and evaluate the effect of it. Methods: The core curriculum for general education of sex and health had be opened to all the students in Shanghai Jiao Tong University from Feb. 2010 to Jun. 2011. The courses imported simulative-situation-learning method. At the end of the semester

to collect and sort the feedback and the suggestion of the students. Results: All groups from the course involved the simulative situation seriously

which includes homosexuality of college students

undesired pregnancy and contraception knowledge

etc. According to the feedback of the courses

most of the students acceptted this kind of teaching method. Conclusion: Interacting learning in simulative situation can obviously increase the interest and enthusiasm of students. Meanwhile

the new courses not only improve the understanding of knowledge for students

but also improve the communication skill and team work ability.