To improve the quality of postgraduate students， school of medicine of Shanghai Jiao Tong University have offered medical molecular genetics course to postgraduates and obtained good teaching efficiency. More than ten professors gave lectures on the academic foreland， leading students to find and solve academic problems and training practical and innovative ability of students. Accord-ing to the questionnaires of evaluation of the course and suggestions from postgraduates in the recent two years， some recommendations for the further teaching reform were proposed， such as using multi-plex teaching models， strengthening communication for teaching information with the students， em-ploying comprehensive evaluation methods and strengthening coordination and management of the course.