Objective　To evaluate the application effect of teaching-picture archiving and communication system （T-PACS） in training image reading ability of eight-year-program students. Methods　Sixty students were divided into two groups： control group （applying traditional teaching method） and experimental group（applying traditional teaching method and T-PACS） when doing clinical medical image reading ability training. Making multimedia teaching movie， clinical image reading teaching and establishing image database by T-PACS were used in experiment group. Mean-while， reading room was set up and classroom teaching and problem-oriented assignments were in-creased. Finally objective evaluation of image recognition ability and questionnaire were used to compare the teaching effect. Measurement data were expressed as x±s. Total scores of image reading were am-alyzed by t test. Full score rates were analyzed by ?字2 test. Results　The results showed that the score of medical image reading ability was higher in experimental group （90.08±4.52） than in control group （86.92±4.68） （P=0.010）. There were differences in respiratory and orthopedic full score rate（P=0.006；P=0.035）. Most students thought that application of T-PACS could effectively improve the teaching and learning quality. Conclusions　Application of T-PACS can improve the medical image reading ability of eight-year-program medical students and is worth further promoting.